Interventional Techniques for the Ablation and Augmentation of Extraspinal Lytic Bone Metastases

This article presents an approach to assess extraspinal metastases, reviews available interventional techniques in use today, and offers example cases as an introductory primer to the thought process used for selecting the appropriate interventional treatment. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Interventional Radiology - Category: Radiology Authors: Tags: Review Article Source Type: research

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Keith Rumley, of Grimsby, was given painkillers when he visited his GP with back pain. His death certificate revealed he had cancer, but his family claim they were kept in the dark about his diagnosis.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
This week, I sat, enthralled in a darkened movie theater watching a story unfold. Before the first scene, the line, “Based on an actual lie,” ran across the screen. The film is called The Farewell and is the story of the lung cancer diagnosis of the filmmaker’s grandmother. Lulu Wang is the director for whom art imitates life. Her alter ego is Billi, played by the actress and rapper Akwafina. Billi adores her Nai Nai (Chinese for grandmother), who assisted in raising her when her parents immigrated to the U.S. when she was a child. She discovers that her grandmother was diagnosed with end stage lung cance...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Grief and Loss Health-related Bereavement grieving Source Type: blogs
Abstract Mas-related G-protein-coupled receptor subtype C (MrgC) has been shown to play an important role in the development of bone cancer pain. Ubiquitination is reported to participate in pain. However, whether MrgC ubiquitination plays a role in bone cancer pain remains unclear. To answer this question, we designed and performed this study. Osteosarcoma cells were implanted into the intramedullary space of the right femurs of C3H/HeJ mice to induce progressive bone cancer pain. MrgC agonist bovine adrenal medulla 8-22 (BAM 8-22) or MrgC antagonist anti-MrgC antibody were injected intrathecally on day 14 after ...
Source: Neurochemical Research - Category: Neuroscience Authors: Tags: Neurochem Res Source Type: research
We report a case of a 46-year-old woman with breast cancer complaining of back pain. 18F-NaF PET/CT images show focal increase uptake at facet joints of L5/S1 vertebrae and both knees joints, suggesting degenerative disease. There is normal variant 18F-NaF uptake noted in the ossification at the falx cerebri. Recognition of normal and abnormal extraosseous 18F-NaF uptake is important for correct interpretation to avoid unnecessary further investigations.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
The back pain and odd growth seemed to indicate cancer. But one doctor had a different idea entirely.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Gallstones laparoscopic cholecystectomy Medicine and Health Doctors Source Type: news
This study aimed to determine the impact of health symptoms on HRQoL in breast cancer patients up to 5  years after diagnosis.MethodsFemales surgically treated for early-stage breast cancer diagnosed between 2012 and 2016 (n = 876) were selected from the Netherlands Cancer Registry and invited for a survey about current health symptoms (‘Symptoms and Perceptions questionnaire’, SaP) and HRQoL (‘EORTC-QLQ-C30’). From the latter, functioning and global health were included. Mean scores were compared to norm p opulation scores (T test). Multivariable linear regression analyses were p...
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
Best way to prevent PFP is to do a variety of sports and build up intensity, and to improve thigh muscle strength Related items fromOnMedica Surgical options must be ‘last resort’ for stress incontinence Falls prevention services are not evidence-based Advise bowel cancer patients to take more exercise Exercise better for back pain than acupuncture say experts New ‘treadmill test’ can predict mortality
Source: OnMedica Latest News - Category: UK Health Source Type: news
AbstractPurpose of ReviewThis review discusses the recent advancements in research on Cannabinoids ’ role in pain, including its use in cancer pain, neuropathic pain, fibromyalgia, headache, visceral pain, postoperative and failed back pain management, and concurrent use with opioids.Recent FindingsCurrent research suggests that a potential role exists for medical cannabis in pain management, although research shows varied effectiveness by the type of pain. Moreover, its coadministration with opioids may result in reduced opioid requirements.SummaryPatients with neuropathic pain, cancer pain, and migraine headache ma...
Source: Current Emergency and Hospital Medicine Reports - Category: Emergency Medicine Source Type: research
In this study, a mouse model of morphine-induced granuloma formation by intrathecal catheterization morphine infusion into the atlanto-occipital membrane of the foramen magnum was established in wild-type mice, MrgprB2 mutant (MrgprB2-/-) mice, and in mast cell-deficient W-sash c-kit mutant (KitW-sh/W-sh) mice. Heat-related pain after surgery was performed to investigate the antipain effect of morphine. H&E staining and immunofluorescence staining of the spinal cord were applied to analyze the mechanism of granuloma formation. Morphine-induced mast cell degranulation was assessed by measuring the Ca2+ influx and mediator r...
Source: Journal of Immunology - Category: Allergy & Immunology Authors: Tags: J Immunol Source Type: research
In conclusion, in the absence of obesity, visceral adipose tissue possesses a pronounced anti-inflammatory phenotype during aging which is further enhanced by exercise. Methods of Inducing Cellular Damage are Rarely Relevant to Aging, and the Details Matter https://www.fightaging.org/archives/2019/08/methods-of-inducing-cellular-damage-are-rarely-relevant-to-aging-and-the-details-matter/ One of the major challenges in aging research is determining whether or not models of cellular or organismal damage and its consequences are in any way relevant to the natural processes of aging. One can hit a brick with...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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