Ascending KLFs in Cardiovascular Biology

Cardiac transcription factor biologists have spent many years identifying transcription factors that function as critical regulators of important cellular processes; however, the challenges in understanding cardiac transcriptional regulatory networks have been formidable. The cardiovascular system is a complex organ system in which component muscle cells must interact with other cells in a coordinated fashion to generate and maintain the heart and vasculature. Within the heart, muscle cells contract to circulate the blood, while specialized muscle cells are required for generation of the heartbeat and electrical propagation of coordinated contractile signals.
Source: Trends in Cardiovascular Medicine - Category: Cardiology Authors: Source Type: research