Picture of Erythema Infectiosum
Title: Picture of Erythema InfectiosumCategory: ImagesCreated: 10/19/2009 1:54:00 PMLast Editorial Review: 12/10/2014 12:00:00 AM
CONCLUSIONS: Although there is a variable clinical spectrum, polyarthralgias and generalized maculopapular rash with fever and anaemia are the typical and most frequent manifestations of primary infection by PVB19 and are usually self-limiting. PMID: 32143947 [PubMed - as supplied by publisher]
Authors: Ruiz Molina I, Chic Acevedo C, Solís García E PMID: 32143942 [PubMed - as supplied by publisher]
Abstract Childhood exanthems are commonly encountered by pediatricians in the hospital and the office. In the last several decades, we have seen a shift in the epidemiology of many of these diseases. After being deemed eliminated at the turn of 21st century, measles has experienced a resurgence secondary to falling vaccination rates, raising public health concerns. A new variant of hand, foot, and mouth disease caused by coxsackievirus A6 has been associated with more widespread and atypical disease, which can present diagnostic challenges to clinicians. Parvovirus B19, which is traditionally associated with fifth...
r V PMID: 32019454 [PubMed - in process]
Parvovirus B19 (PVB19) is a single-stranded DNA virus that infects erythroid progenitor cells, classically causing a pure red cell aplasia, but sometimes causing fulminant pancytopenia. PVB19 has been implicated in solid organ allograft failure, but no such literature exists for allogeneic hematopoietic stem cell transplantation (allo-HSCT). PVB19 may be an underappreciated complication in allo-HSCT.
Authors: Su CC, Hsu TC, Hsiao CH, Chiu CC, Tzang BS Abstract Human parvovirus B19 (B19V) infection has symptoms similar to those of anti‑phospholipid syndrome (APS). Antibodies against B19V‑VP1 unique region (VP1u) exhibit activity similar to that of anti‑phospholipid antibodies (aPLs) by inducing vascular endothelial cell adhesion factors and APS‑like syndrome. Previous studies have identified an effect of aPLs on angiogenesis. However, little is understood regarding the effect of anti‑B19V‑VP1u antibodies on angiogenesis. The present study investigated the effects of anti‑B19V‑VP1u ...
ConclusionsB19V ‐PCR positivity was high and similar in both cases and controls. In our study B19V‐DNAemia was thus not seen to be associated with fatal outcome of pregnancy. The clinical significance of B19V‐DNA detection during pregnancy is uncertain. Caution is needed when diagnosing a B19V‐infection bas ed only on B19V‐DNAemia.
Publication date: Available online 6 January 2020Source: Clinics and Research in Hepatology and GastroenterologyAuthor(s): Nicolas Gille, Anne-Marie Roque-Afonso, Mylène Sebagh, Marika Rudler, Dominique Thabut, Jean-Charles Duclos-Vallée, Didier Samuel, Audrey Coilly
ConclusionCardiotropic viruses (HHV6, Parvovirus B19 and Coxsackie virus) were found in almost 50% of cases in “infarct like” acute myocarditis. According the presence or absence of cardiotropic viruses, CMR parameters were different. Furthermore, use of quantitative PCR (detection of viral genomes) or detection of viral DNA and RNA via in situ hybridization would be a challenge for the future identification of viruses in myocarditis.