Efficacy of Platelet Rich Fibrin Versus Chitosan as A Hemostatic Agent Following Dental Extraction in Patients on Antiplatelet Therapy.

Publication date: Available online 18 August 2019Source: Journal of Oral Biology and Craniofacial ResearchAuthor(s): Sourav Sarkar, N.T. Prashanth, E.S. Shobha, Vinod Rangan, G. NikhilaAbstractObjectivesThe aim of this study is to compare the effectiveness of Platelet Rich Fibrin gel and Chitosan gel dressing in providing hemostasis in patients receiving Oral Antiplatelet Therapy and also to evaluate their surgical healing outcome following dental extractions.MethodologyA total of 60 patients under Oral Antiplatelet Therapy indicated for tooth extraction were included for treatment in the study without altering the oral antiplatelet regimens. Patients were allocated equally in two groups; Group A: where PRF gel was packed into the extraction socket, while Group B: Chitosan hydrogel was packed. Timing of hemostasis was noted for each patient of both the groups. Patients were examined for any pain/ secondary bleeding/ healing/ soft tissue dehiscence/ alveolar osteitis in the extraction site on first, third and seventh post-operative days.ResultsAll extraction sockets with Platelet-rich fibrin achieved hemostasis in 2.64 minutes and sockets with Chitosan hydrogel achieved hemostasis in 1.182 minutes (p
Source: Journal of Oral Biology and Craniofacial Research - Category: Dentistry Source Type: research

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ConclusionsEndovascular coil fiducial placement for lung SBRT is associated with high procedural success rates and lower rates of clinically relevant complications than transthoracic marker placement.
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
Patients who have undergone endometrial ablation may present a diagnostic challenge when they present years later for vaginal bleeding, pelvic pain or postmenopausal bleeding. Extensive scarring of the uterine cavity often precludes evaluation and/or conservative treatment. To further research this topic, we performed a hysteroscopic examination a mean 4 years after study subjects had undergone water vapor endometrial ablation.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Source Type: research
Publication date: Available online 13 September 2019Source: Saudi Journal of Biological SciencesAuthor(s): Lixia Zhang, Gang Wang, Jianhui Gan, Zhongci Dou, Liying BaiAbstractObjectiveTo elaborate the analgesic efficiency of midazolam-induced anesthesia in different doses on the patients following the thoracoscopic resection of lung cancer.MethodsNinety patients undergoing thoracoscopic resection of lung cancer between August 2017 and July 2018 were randomized in the observation group (n=45) and the control group (n=45). Patients in observation group underwent the anesthesia induced by 0.1 mg/kg midazolam, while for the co...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
r M Abstract OBJECTIVE: Fast track concepts are used to reduce the risk of perioperative and postoperative complications after total knee arthroplasty. INDICATIONS: The described concepts are used for patients with indications for the implantation of a total knee prosthesis. CONTRAINDICATIONS: Contraindications for fast track concepts are aged patients, dementia, American Society of Anesthesiologists (ASA) grade IV and implantation of large revision or tumor prostheses. Contraindications for tranexamic acid are bleeding in the urinary tract, caution in cases of known epilepsy, individual risk assessment ...
Source: Operative Orthopadie und Traumatologie - Category: Orthopaedics Authors: Tags: Oper Orthop Traumatol Source Type: research
We report a case of intolerance to warfarin. A 20-year-old woman with toe pain was diagnosed as myxoma with multiple systemic embolism. She was prescribed warfarin for remaining embolic pain after myxoma excision and mitral annuloplasty. Even on 1 mg of warfarin, INR was much increased. The patient have the Cytochrome P450 2C9 (CYP2C9)*3/*3 and vitamin K epoxide reductase complex subunit 1 (VKORC1) 1639AA genotype, extremely rare in Koreans. Based on this result, we assessed the potential risks and benefits of warfarin, and decided to switch to aspirin because the risk of bleeding was considered to be too high.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
We describe two Japanese brothers with immunoglobulin-A vasculitis (IgAV) who met the diagnostic criteria of LAHPS. They presented with palpable purpura and abdominal pain, and had a prolonged activated partial thromboplastin time (APTT) and prothrombin deficiency with the presence of lupus anticoagulant. Pediatric LAHPS was reviewed in abstracts from the Japan Medical Abstracts Society that were written in Japanese and PubMed or Web of Science-listed articles in English between 1996 and 2019. Including our cases, pediatric LAHPS has been reported in 40 Japanese and 46 non-Japanese patients. We summarized the clinical and ...
Source: Rheumatology International - Category: Rheumatology Source Type: research
We report a case of intolerance to warfarin. A 20-year-old woman with toe pain was diagnosed as myxoma with multiple systemic embolism. She was prescribed warfarin for remaining embolic pain after myxoma excision and mitral annuloplasty. Even on 1 mg of warfarin, INR was much increased. The patient have the Cytochrome P450 2C9 (CYP2C9)*3/*3 and vitamin K epoxide reductase complex subunit 1 (VKORC1) 1639AA genotype, extremely rare in Koreans. Based on this result, we assessed the potential risks and benefits of warfarin, and decided to switch to aspirin because the risk of bleeding was considered to be too high. PMID: ...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
Sala Abdalla, Tayo OkeJournal of Minimal Access Surgery 2019 15(4):339-341A Meckel's diverticulum (MD) is a congenital abnormality of the gastrointestinal tract which is estimated to be present in 2% of the population. Gastrointestinal stromal tumours (GISTs) are rare, soft-tissue tumours which represent 0.1%–3% of all gastrointestinal tumours. The association of an MD and a GIST is extremely unusual since fewer than 3% of MD harbour primary neoplasms and most of these neoplasms are carcinoid tumours. While MDs may remain asymptomatic throughout life, a small proportion may be complicated by occul...
Source: Journal of Minimal Access Surgery - Category: Surgery Authors: Source Type: research
ConclusionsThe use of intraoperative ketorolac is a useful adjunct in perioperative pain management in breast surgery and does not increase the risk of bleeding.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
We report a case of a 66-year-old man with abdominal pain, hematochezia and clots in the left colon, without any radiologic signs of active bleeding or bowel occlusion or analytical changes in routine coagulation screening, but with positive autoantibodies against factor VIII. The clinical instability prompted surgical exploration. An intramural hematoma of the left colon was found, and a left colectomy was performed. The patient was treated with hemoderivatives and corticosteroids with clinical improvement. The diagnosis of spontaneous intramural hematoma might be a challenge, particularly in the absence of clin...
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
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