SLU researchers to address need for new pain medicine with $2.1M grant

A Saint Louis University pain researcher has received a $2.1 million grant from the National Institutes of Health to investigate a pain signaling pathway in order to help open up a new avenue for pain medication research, officials said. Dr. Daniela Salvemini has spent her career studying chronic neuropathic pain in order to help find new ways to treat it without opioids. Neuropathic pain affects between 15 and 20 million people in the U.S. This type of pain happens after injuries to the nervous…
Source: Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news

Related Links:

Conditions:   Headache Disorders, Secondary;   Post-Dural Puncture Headache;   Migraine Disorders;   Back Pain;   Anesthesia Intervention:   Sponsor:   Stanford University Active, not recruiting
Source: - Category: Research Source Type: clinical trials
Source: Mindfulness - Category: Psychiatry & Psychology Source Type: research
Publication date: Available online 20 August 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Megan N. Wasson
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
World's First Commercial Implants of the Evoke System Completed in The Netherlands ARTARMON, Australia, Sept. 16, 2019 -- (Healthcare Sales &Marketing Network) -- Saluda Medical Pty Limited ("Saluda Medical") today announced the award of CE ... Devices, Regulatory, Product Launch Saluda Medical, Evoke , Spinal Cord Stimulation
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
The objective of this study was to evaluate the potential analgesic action of 8% capsaicin cream for topical use in patients with myofascial pain syndrome. METHODS: Initially, cream formulations of PLA (Placebo) and CPS (Capsaicin 8%) were developed and approved according to the current requirements of the health authority agency. The 40 participating patients were randomly assigned to the PLA and CPS groups in a double-blind fashion. Before the creams were topically administered, according to the allocation group, the local anesthetic was used for a period of 50minutes directly in the area of interest. The cream was a...
Source: Revista Brasileira de Anestesiologia - Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research
Publication date: Available online 14 September 2019Source: Reumatología Clínica (English Edition)Author(s): Manuel Jiménez Ortiz, Alfonso Espinosa Ruiz, Cristóbal Martínez Delgado, Pablo Barrena Sánchez, José A. Salido ValleAbstractBackgroundThe association of depression and chronic pain in knee osteoarthritis is a complex and difficult phenomenon to understand. In fact, establishing the order of appearance of these entities might result in an arduous task.ObjectiveIn addition to analysing the relationship between preoperative anxiety and depression according to the results...
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research
In conclusion, miR-101 had neuropathic pain-attenuating activity through targeting mTOR.
Source: Neuroscience Research - Category: Neuroscience Source Type: research
As a GP, I know opioids have their place. But we shouldn ’t be complacent about a US-style crisis happening in BritainGrowing concern about the prescription of drugs that cause dependence has been backed up by a recent report from Public Health England (PHE). The agencydiscovered that in 2017-18, 13% of adults in England received at least one prescription for opioids such as morphine or oxycodone (although this represented a slight downturn in prescribing after a long upward trend). Other drug classes were implicated too, with 25% of adults prescribed one or more of the following drugs: benzodiazepines (such as Valiu...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Opioids GPs NHS Doctors Health Society Drugs policy Politics Science UK news Source Type: news
Source: Psychology, Health and Medicine - Category: International Medicine & Public Health Authors: Source Type: research
Many people suffer from a major depressive disorder, and chronic pain conditions are often associated with depressive symptoms. Neurotropin, an extract from the inflamed skin of rabbits inoculated with vaccinia virus, has been used for pain relief. Decrease of brain-derived neurotrophic factor (BDNF) in the brain is one of the proposed mechanisms for the major depressive disorders, and Neurotropin has been reported to restore the decreased BDNF in the hippocampus. In this experiment, we examined whether Neurotropin had an antidepressant-like effect in a model of fibromyalgia and whether BDNF in the brain was altered after ...
Source: Behavioural Pharmacology - Category: Drugs & Pharmacology Tags: Research Reports Source Type: research
More News: Biotechnology | Brain | Chronic Pain | Grants | Health Management | National Institutes of Health (NIH) | Neurology | Pain