C. auris in a U.S. Patient Recently Hospitalized in Kenya C. auris in a U.S. Patient Recently Hospitalized in Kenya

This case of a patient colonized with Candida auris after extended hospitalization in Kenya underscores how health care exposure outside the US is a risk factor for emerging drug-resistant infections.Morbidity &Mortality Weekly Report
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Public Health & Prevention Journal Article Source Type: news

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Publication date: Available online 12 September 2019Source: Biotechnology ReportsAuthor(s): Juliya Johny, Venkateshwarlu Kontham, Dileep Veeragoni, Sunil Misra, Shiva Shanker KakiAbstractThe first synthesis of a phenolic natural monoacylglycerol (1- [11-(ferulyloxy) undecanoyl)] glycerol) was carried out by bioorganic synthesis starting from ferulic acid. The synthetic route of the target lipidic compound was designed involving a chemo-enzymatic approach using immobilized Candida antarctica lipase as biocatalyst in two of the steps conducted in organic medium. The prepared lipidic compound was characterized by using spectr...
Source: Biotechnology Reports - Category: Biotechnology Source Type: research
Publication date: Available online 12 September 2019Source: Protein Expression and PurificationAuthor(s): Lisette Van Tassel, Antti Moilanen, Lloyd W. RuddockAbstractCandida antarctica lipase B (CalB) is a very efficient catalyst and is used in a wide range of industries from food flavour to pharmaceutical, and biodiesel manufacturing. It has a high degree of enantioselective and regioselective substrate specificity and is stable over a wide range of biophysical conditions including pH, temperature and solvent conditions. High-level expression of biologically active wild-type CalB has been problematic, partly due to foldin...
Source: Protein Expression and Purification - Category: Biochemistry Source Type: research
Conclusion: We found few genetically-related as well as identical isolates among the 32 Candida strains which indicated low cross-contaminations among the patients. There was no relationship between C. albicans MLST profiles and their geographic distribution, cancer type and SAP2 gene expression. This lack of correlation was possibly due to the small understudy population; hence, finding more relevance requires studies with a higher number of samples.
Source: Journal of Medical Mycology - Category: Biology Source Type: research
Publication date: Available online 11 September 2019Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Wenbin Jin, Yan Xu, Xiao-Wei YuAbstractSupported cross-linked enzyme aggregates were prepared by immobilization of Candida antarctica lipase B onto hydrophobic surface of octyl-modified mesocellular foams (MCFs-C8). Oxidized sodium alginate was used as a substitute for traditional glutaraldehyde. Supported cross-linked enzyme aggregates using oxidized sodium alginate (SA-CLEAs@MCFs-C8) exhibited significantly improved thermal stability and organic solvents tolerance compared to the free lipase, lipase adsorbed onto ...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
The antimicrobial and antifungal activities of maleopimaric acid (MPA) and several of its 2- and 6-derivatives were investigated. An analysis of the results showed pronounced antimicrobial activity for 2-allylmaleopimarimide and MPA N-benzylcarboxamide against test strains of Gram-negative and Gram-positive microorganisms and antifungal activity of 2-allylmaleopimarimide against lower-fungus test strain Candida albicans. New methods for producing MPA N-benzylcarboxamide and N-hydroxymaleopimarimide that increased the yields of target products were proposed.
Source: Chemistry of Natural Compounds - Category: Chemistry Source Type: research
utarowska Studies on the functionalization of materials used for the construction of filtering facepiece respirators (FFRs) relate to endowing fibers with biocidal properties. There is also a real need for reducing moisture content accumulating in such materials during FFR use, as it would lead to decreased microorganism survival. Thus, in our study, we propose the use of superabsorbent polymers (SAPs), together with a biocidal agent (biohalloysite), as additives in the manufacturing of polypropylene/polyester (PP/PET) multifunctional filtering material (MFM). The aim of this study was to evaluate the MFM for stability...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Drug-resistant germs, including Candida auris, prey on severely ill patients in skilled nursing facilities, a problem sometimes amplified by poor care and low staffing.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Nursing Homes Drug Resistance (Microbial) Candida Auris (Fungus) Antibiotics Hygiene and Cleanliness Protective Clothing and Gear Palm Gardens Center for Nursing and Rehabilitation (Brooklyn, NY, Nursing Home) your-feed-science Source Type: news
This article reviews infection control and treatment strategies to manage Candida auris, a new drug-resistant fungal species that can cause severe invasive infection with high morbidity and mortality in patients with underlying comorbid illnesses.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Drug-resistant germs, including Candida auris, prey on severely ill patients in skilled nursing facilities, a problem sometimes amplified by poor care and low staffing.
Source: NYT Health - Category: Consumer Health News Authors: Tags: your-feed-science Drug Resistance (Microbial) Candida Auris (Fungus) Nursing Homes Antibiotics Elderly Elder Care Hygiene and Cleanliness Protective Clothing and Gear Palm Gardens Center for Nursing and Rehabilitation (Brooklyn) Source Type: news
Updated Date: Thu, 12 Sep 2019 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
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