Transcendental Meditation and Hypothalamic-Pituitary-Adrenal Axis Functioning: A Pilot, Randomized Controlled Trial with Young Adults.

Transcendental Meditation and Hypothalamic-Pituitary-Adrenal Axis Functioning: A Pilot, Randomized Controlled Trial with Young Adults. Stress. 2019 Aug 16;:1-33 Authors: Klimes-Dougan B, Chong LS, Samikoglu A, Thai M, Amatya P, Cullen KR, Lim KO Abstract Transcendental Meditation (TM) is effective in alleviating stress and anxiety and promoting well-being. While the underlying biological mechanisms of TM are not yet fully explored, the hypothalamic-pituitary-adrenal (HPA) axis represents an index providing important clues embodying the stress system cascade. In this pilot study, young adults were randomly assigned to TM training followed by eight weeks of meditation practice or a wait-list control condition. TM was conducted over eight weeks. Thirty-four young adult participants were randomized; 27 participants completed the HPA outcome assessments (41% male). To assess HPA axis functioning, salivary samples to assess cortisol awakening response (CAR) that were collected in the morning, both at baseline and at week-4. Salivary cortisol in the context of a social stressor using the Trier Social Stress Test (TSST) was collected at week-8. The results indicate that participants who were randomly assigned to TM had lower awakening salivary cortisol levels and a greater drop in CAR from baseline to week-4 than the control group. There were no significant differences in HPA axis functioning in the context of the TSST. Primary limitations of this randomized cont...
Source: Stress - Category: Research Tags: Stress Source Type: research

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Conclusion/Importance: This study indicates that future research should take into account substance use patterns in adults engaging in NSI behaviors. PMID: 31519128 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
Publication date: Available online 14 September 2019Source: Journal of Psychiatric ResearchAuthor(s): Ruijia Chen, Ronald C. Kessler, Ekaterina Sadikova, Amanda NeMoyer, Nancy A. Sampson, Kiara Alvarez, Corrie L. Vilsaint, Jennifer Greif Green, Katie A. McLaughlin, James S. Jackson, Margarita Alegría, David R. WilliamsAbstractThe purpose of this study was to: (1) examine the associations of individual-level objective socioeconomic status (OSS), subjective socioeconomic status (SSS), and area-based indicators of socioeconomic status, with 12-month DSM-IV mood, anxiety, alcohol use, and drug use disorders; and, (2) de...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: Available online 14 September 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Santiago J. Ballaz, Michel Bourin, Huda Akil, Stanley J. WatsonAbstractCholecystokinin (CCK), through the CCK-2 receptor, exerts complex effects on anxiety. While CCK agonists are panicogenic, CCK-2 antagonists fail to alleviate human anxiety. Preclinical studies with CCK-2 antagonists are also inconsistent because their anxiolytic effects largely depend on the behavioral paradigm and antecedent stress. The controversy might be accounted by the neuromodulatory role for CCK in anxiety which is...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
ConclusionsOur findings suggest a dose-effect mechanism modulating the relationship between treatment-related SI and AS. AS symptoms may need to be monitored closely in the weeks that follow the introduction of an antidepressant treatment.
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Conclusion: Gabapentin as an adjunctive drug could be more effective in reducing the severity of GI symptoms in patients with dyspepsia, especially neurological symptoms (such as pain, reflux, and indigestion). PMID: 31516891 [PubMed]
Source: Biomed Res - Category: Research Authors: Tags: Adv Biomed Res Source Type: research
Could anyone here please mention any programs where they might have seen a non US IMG among the residents? Found about 34 programs from EMRA + about 10 more with extensive googling. I think less than 15 non US IMG's matched last year if you exclude the sponsored middle eastern candidates. I know I'll probably end up applying to all programs that exist, cos non-US IMG's can't be choosers, but eras anxiety made me post this
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Emergency Medicine Source Type: forums
In males of a variety of species, administration of progesterone during adulthood has been shown to decrease the expression of consummatory sexual behaviors and androgen receptors. However, it remains to be determined if the progesterone-induced decrease in androgen-receptor signaling and consummatory sexual behaviors correspond with less of a preference for a sexually receptive female relative to another male, a behavioral phenotype indicative of sexual motivation. Consistent with the effects of progesterone reported in males of other species, progesterone-treated rats, relative to vehicle-treated rats, exhibited fewer in...
Source: Behavioural Pharmacology - Category: Drugs & Pharmacology Tags: Short Report Source Type: research
Previously observed antidepressant-like effects of caffeine in adolescent rats have been shown in individually housed (IH) rats. Because IH presents a social stressor that may create depressant-like effects in control animals, this study sought to compare the effects of chronic caffeine in IH and pair-housed (PH) adolescent male and female rats. Housing conditions began on postnatal day 24 (P24) and half of the rats were provided caffeine (0.25 g/l) in their drinking water beginning on P28. Open-field behavior was assessed on P42, a light/dark test was conducted on P43, and a forced swim test was conducted on P44–P45...
Source: Behavioural Pharmacology - Category: Drugs & Pharmacology Tags: Research Reports Source Type: research
US suicide rates have risen by 41 percent in just three years. → Support PsyBlog for just $4 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Suicide subscribers-only Source Type: blogs
Around half the world’s population is deficient in vitamin D. → Support PsyBlog for just $4 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Weight Loss Source Type: blogs
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