Diffusion-weighted MRI with ADC mapping for response prediction and assessment of oesophageal cancer: A systematic review

Oesophageal cancer is a malignancy with a poor prognosis, as reflected by an average overall 5-year survival of only 18% [1]. Locally advanced oesophageal cancer patients are generally treated by chemo- and/or radiotherapy, either as definite treatment or as neoadjuvant treatment prior to surgery [2 –4]. However, not all patients benefit equally. In 23% of adenocarcinomas (AC) and 49% of squamous cell carcinomas (SCC) a pathological complete response (pCR, tumour regression grade (TRG) 1) is determined on histopathology of the resection specimen after neoadjuvant chemoradiotherapy (nCRT) [2,5 ].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Systematic Review Source Type: research