LncRNA-ROR is involved in cerebral hypoxia/reoxygenation-induced injury via regulating miR-135a-5p/ROCK1/2.

In conclusion, this study indicated that LncRNA-ROR could promote the cerebral H/R injury by inhibiting the expression of miR-135a-5p through upregulating the expression of ROCK1/2. And, miR-135a-5p overexpression could improve the cerebral H/R injury by inhibiting the expression of ROCK1/2. PMID: 31419405 [PubMed - as supplied by publisher]
Source: Experimental and Molecular Pathology - Category: Pathology Authors: Tags: Exp Mol Pathol Source Type: research