Targeting Serotonin1A Receptors for Treating Chronic Pain and Depression.

This article targets the 5-HT1A receptors to show that indiscriminate activation of pre and postsynaptic 5-HT1A receptors is likely to produce no therapeutic benefits; biased activation of the 5-HT heteroreceptors may be a useful strategy for treating chronic pain and depression individually as well as in the comorbid condition. PMID: 31418663 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31418663?dopt=Abstract

Source: Current Neuropharmacology - August 10, 2019 Category: Drugs & Pharmacology Authors: Haleem DJ Tags: Curr Neuropharmacol Source Type: research