Resolution of acute lower extremity deep vein thrombosis with rivaroxaban compared to warfarin

AbstractThrombosis resolution is an important component of treatment for deep vein thrombosis (DVT) and multiple anticoagulants are now available. It is unknown whether rivaroxaban contributes to a higher degree of thrombus resolution compared to conventional anticoagulation with warfarin. Our objective was to compare thrombus resolution for rivaroxaban versus warfarin treated patients with acute lower extremity DVT. Consecutive patients treated for proximal or distal lower extremity DVT with rivaroxaban were identified from the Mayo Thrombophilia Clinic Anticoagulants Registry (November 2015 –June 2016) and compared to patients treated with warfarin. Ultrasonography/Doppler images were analyzed by two independent radiologists blinded to anticoagulant and using a standardized assessment algorithm. A total of 111 patients with DVT were studied. Sixty-three rivaroxaban treated patients w ere compared to 48 warfarin treated patients over a median follow up of 92 and 97 days, respectively. Percentage of patients with total or partial resolution of thrombosis was similar in rivaroxaban and warfarin treated groups (95.2% vs. 91.7%, p = 0.46, respectively); also the proportion of pa tients with total thrombus resolution was not significantly different (38.1% vs. 29.2%, p = 0.42, respectively). There was no significant difference in the proportion of patients with no thrombus resolution between rivaroxaban and warfarin treated groups either (4.8...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research

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AbstractIn the existing reports on combined procedures of abdominoplasty with Cesarean section or natural delivery, a high incidence of complications and poor aesthetic results are reported. We conducted a survey with the participation of 61 plastic surgeons who performed this procedure in 808 patients, with an average of 13.24 procedures per surgeon. In 783 procedures (96.9% of the cases), the combination was with Cesarean section and 25 procedures (3.13% of cases) were combined with vaginal delivery. The plastic surgery procedures were as follows: 242 abdominoplasty procedures (29.95%), 210 abdominoplasty plus liposuctio...
Source: Aesthetic Plastic Surgery - Category: Cosmetic Surgery Source Type: research
Authors: Xu X, Guo X, Wang R, Wang L, Li Q, Yi F, Li H, Qi X Abstract Acute portomesenteric vein thrombosis is potentially lethal. In the present paper, a cirrhotic patient with a previous history of esophageal variceal bleeding presented with acute occlusive portomesenteric vein thrombosis, but achieved complete recanalization by low-molecular-weight heparin followed by rivaroxaban. Notably, no bleeding episode occurred during anticoagulation therapy. This case supported early initiation of anticoagulation in such patients. PMID: 31521463 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Recently, studies showed that neutrophils extracellular traps (NETs) are the fiber network structures formed by the materials released by neutrophils under various appropriate stimulation. NETs have been indicated to trap and kill microorganisms, playing a critical role in immune responses. It was pointed out that NETs can not only be involved in inflammation and thrombosis, but also is intimately related to tumor metastasis. Therefore, the study of NETs in tumor metastasis is of great significance for tumor therapy and the progress of NETs in tumor metastasis and the relevant mechanisms is summarized. 
 DOI: 10.3779/j.i...
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
AbstractPurposeNovel oral anticoagulants are increasingly replacing vitamin K antagonists in the prophylaxis of thromboembolism as they are associated with lower incidence of spontaneous intracerebral hematomas and they do not require drug level monitoring. However, management dilemmas are apparent in patients on novel oral anticoagulants who have developed intracerebral hematomas after traumatic brain injury, since clinical experience with their reversal strategies is limited.MethodsWe retrospectively studied 90 patients with traumatic intracerebral hematomas undergoing treatment at the surgical intensive care unit of the...
Source: European Journal of Trauma and Emergency Surgery - Category: Emergency Medicine Source Type: research
This Case aimed to explore the clinical, histological, and immunohistochemical features of intravascular fasciitis (IVF) that involve a large blood vessel.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
In this report, we present a case of acquired pelvic and lower extremity AVFs following left common iliac vein (CIV) thrombosis. The special feature of this case is that the patient received a series of treatments of which recanalization resulted in best clinical outcome.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
Calcification is closely related to in situ thrombosis secondary to plaque rupture in the coronary artery. However, the association between calcification in lower extremity arteries and acute thrombosis has not been assessed. We thus sought to determine whether lower limb arterial calcification (LLAC) was correlated with acute thrombosis in patients with symptomatic peripheral artery disease (PAD).
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Clinical Research, Basic Science Source Type: research
This study was to investigate the incidence of pulmonary embolism (PE) in a cohort of Chinese patients with acute (
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Clinical Research, Basic Science Source Type: research
AbstractFinding optimal parameters of endovenous laser coagulation using the radiation with a wavelength of 1910  nm. In vivo experiments have been carried out on the small saphenous veins of three sheep of Edilbay breed and the dependence of venous wall and surrounding tissue damage on the radiation power was analyzed on the basis of morphological study results, as well as ultrasound examination and clinical observation of animals in the postoperative period. As radiation source, we used the diode-pumped solid-state laser, based on the LiYF4:Tm crystal, with emission wavelength of 1910  nm. For morphological stu...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
ConclusionsNeedle aspiration of the ganglion was performed, and swelling of the lower extremity promptly decreased. At 7.5 years after aspiration, there was no recurrence of swelling of the leg. Although the recurrence rate for ganglions after needle aspiration is high, it is worthwhile trying aspiration first.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
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