Ultrasound diagnosis of pancreatic solid tumors

ConclusionCEUS is a minimally invasive and useful diagnostic method that can be used to make a simple and quick qualitative diagnosis of pancreatic diseases. CEUS provides a lot of information important for diagnosis, and has led to changes in the conventional diagnostic systems in pancreatic diseases.
Source: Journal of Medical Ultrasonics - Category: Radiology Source Type: research

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ConclusionsManagement of SNAC consists of histological diagnosis, radiological staging, radical surgery, and adjuvant radiation therapy. Neoadjuvant chemotherapy can be indicated in selected cases. The role of biotherapy and immune therapy still needs to be elucidated.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
We reported a case of 18 years-old female patient admitted to Mansoura oncology center with severe abdominal pain. Physical examination revealed a distended abdomen with hepatomegaly with no abdominal mass. Computed tomographic (CT) scan of the abdomen revealed markedly enlarged liver with multiple innumerable variable sized hyper-echoic non-enhanced focal lesions. The patient underwent an ultrasound- guided biopsy of the liver that showed metastatic yolk sac tumor. Colonoscopy confirmed a large polypoidal ulcerating mass that was 15 cm from anal verge. Biopsy from the mass revealed conventional colonic adenocarcinoma merg...
Source: Current Medicine Research and Practice - Category: General Medicine Source Type: research
ConclusionsThe data obtained in this study confirmed a potent anti-tumor efficacy caused by the ACA nanoplatform and ultrasound combination. It may provide a beneficial cancer therapy strategy in which the thermal and mechanical effects of ultrasound can intensify the therapeutic ratio of conventional chemotherapy methods.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 21 September 2019Source: Cirugía Española (English Edition)Author(s): Alexis Luna Aufroy, Salvador Navarro SotoAbstractPreoperative clinical staging is critical to select those patients whose disease is localized and may benefit from surgery with curative intent. Ideally, such staging should predict tumor invasion, lymphatic involvement and distant metastases. With the cTNM, we are able to select patients who could benefit from endoscopic resection, radical surgery or less radical treatment in patients with distant metastasis. The initial diagnosis of adenocarcinomas of the ...
Source: Cirugia Espanola - Category: Surgery Source Type: research
Abstract Preoperative clinical staging is critical to select those patients whose disease is localized and may benefit from surgery with curative intent. Ideally, such staging should predict tumor invasion, lymphatic involvement and distant metastases. With the cTNM, we are able to select patients who could benefit from endoscopic resection, radical surgery or less radical treatment in patients with distant metastasis. The initial diagnosis of adenocarcinomas of the esophagogastric junction requires endoscopy with biopsies. For clinical staging, thoracoabdominal-pelvic CT scan, endoscopic ultrasound and PET or PET...
Source: Cirugia eEspanola - Category: Surgery Authors: Tags: Cir Esp Source Type: research
This study reports the findings from 9 sheep that received sensor implantations. Time taken from initial CT scans to the placement of a single sensor into an OPA tumour was 45 ± 5 min, with all implantations resulting in the successful delivery of sensors into tumours. Immediate post-implantation mild pneumothoraces occurred in 4 sheep, which was successfully managed in all cases. This is, to the best of our knowledge, the first description of the use of naturally-occurring OPA cases as a pre-clinical surgical model. Through the integration of techniques used in the treatment of human lung cancer patients, including...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Patients diagnosed with esophageal adenocarcinoma (EAC) undergo multimodality evaluation with EUS for locoregional staging and PET/CT scan for detection of metastatic disease. For patients with potentially resectable disease, those staged with T1/T2 and N0 are treated by endoscopic resection or esophagectomy only whereas neoadjuvant therapy followed by esophagectomy is recommended for patients staged with T1/T2 but N positive or T3/T4 with any N status. However, the role of EUS in T1 and T2 staging is limited and is not routinely needed in all patients with EAC.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Sunday abstract Source Type: research
Conclusions: Correlation between 18F-FDG SUVpeak and SULpeak in liver metastases from colorectal adenocarcinoma and KRAS missense mutation status is seen in a cohort of 23 patients who underwent PET/CT guided biopsies. Applying PVE corrections was critical for obtaining borderline statistical significance of this correlation. The accuracy of these findings may be improved if the study is focused only on cases for which a molecular pathology report is available for each analyzed lesion. Therefore, accumulating a larger cohort of such cases as well as including more markers may allow better separation of MetCRC liver lesions...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: GI & amp;acirc; amp;euro; ' Colorectal, Liver, Esophageal Source Type: research
Conclusions: There has been no study evaluating the use of 18-FDG PET/CT in tandem with CA 19-9 to diagnose early stage pancreatic adenocarcinoma. Using the same principles previously applied to HIV diagnosis where a sensitive and relatively less expensive screening blood test (i.e., ELISA) would be used in tandem with a specific but more expensive confirmatory test (i.e., Western blot), it is proposed that early-stage pancreatic adenocarcinoma may be diagnosed in tandem similarly. When the threshold for CA 19-9 is lowered to 32 units/mL, the blood test can be used as a screening test for pancreatic adenocarcinoma since th...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: GI & amp;acirc; amp;euro; ' Pancreatic amp; Neuroendocrine Source Type: research
CONCLUSIONS: Penile localization is an extremely rare event and a standard of care has not been elaborated. Treatments are palliative and mainly aimed at pain relief and can comprise chemotherapy, radiotherapy, and surgery. Identification of venous thrombosis as an early sign of involvement could potentially offer patients an earlier diagnosis and a better treatment option. PMID: 31072230 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
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