It's Not The Number of Pills--It's The Number of Deaths That Matter

A  letter to the editor in the August 14 New England Journal of Medicine by researchers at the University of Michigan proudly reported on the results of their effort, called the Michigan Surgical Quality Collaborative (MSQC), to reduce the volume of opioids prescribed for postoperative pain. The Collaborative developed a set of guidelines for its participating prescribers.As a result, they found that from January 2017 through May 2018, the mean number of pills prescribed for postoperative pain decreased from 26 (+/-2) pills pre-guideline to 18 (+/ – 3) pills post-guideline. Patient pill consumption also decreased from an average of 12 pills (+/-1) pre-guideline to 9 pills (+/-2) post-guideline. During that period there was no discernible difference in the pain scores reported by these patients pre-and post-guideline.It seems all of health care  is now fixated on getting the number of prescription pain pills down. Yet there is no correlation between prescription volume and nonmedical use or use disorder/addiction. And as prescription volume has dramatically come down since 2010, the overdose rate has dramatically  increased. Furthermore, in 2017 at least 75% of opioid-related overdoses were from heroin or fentanyl, while 40% of overdoses involving prescription opioids had multiple other drugs onboard, including heroin, fentanyl, alcohol, and tranquilizers.So, as academic physicians continue to virtue signal and show the media and regulators ...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs

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AbstractGlobally, chronic pain is a major therapeutic challenge and affects more than 15% of the population. As patients with painful terminal diseases may face unbearable pain, there is a need for more potent analgesics. Although opioid-based therapeutic agents received attention to manage severe pain, their adverse drug effects and mortality rate associated with opioids overdose are the major concerns. Evidences from clinical trials showed therapeutic benefits of cannabis, especially delta-9-tetrahydrocannabinol and cannabinoids reduced neuropathic pain intensity in various conditions. Also, there are reports on using co...
Source: Journal of Anesthesia - Category: Anesthesiology Source Type: research
While Suboxone can be a helpful tool for many, it is important to also understand its addictive nature. Because it is an opioid, wondering if you can form an addiction to Suboxone can be answered simply: Yes. Although the rates of addiction are much smaller than those of other opioids, it is still important to take their addictive properties seriously and get help if you start to notice the signs and symptoms of addiction to Suboxone. What is Suboxone? According to their own website, Suboxone is a prescription medicine that contains the active ingredients buprenorphine and naloxone. It is used to treat adults who are depe...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction to Pharmaceuticals Substance Abuse addiction treatment addictionologist detox drug detox medical detox medicated-assisted detox prescription drug detox prescription medication suboxone Source Type: blogs
Abstract Endogenous opioids are neuro-peptides with multifunctional properties. Historically, opioids are used to mediate pain; however, excess opiate consumption can lead to addiction. One endogenous opioid, methionine enkephalin (MENK), was reported to modulate cell growth, MENK was identified as an opioid growth factor (OGF) that interacts with the OGF receptor (OGFr) and regulates cell proliferation. Further, opioid antagonists, including naltrexone and naloxone are widely used to reverse drug and alcohol overdoses. Naltrexone (NTX) acts on all opioid receptors, blocking the interaction between OGF and OGFr, a...
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Tags: Int Immunopharmacol Source Type: research
With  clear evidence that restricting the number of prescriptions increased the death rate by driving non-medical users to heroin and fentanyl, the last thing one wants to hear about is a politician planning to double down on this deadly policy by calling for further prescription limits for patients in pain.Yet Senator Robert Portman (R-OH) is  proposing legislation that would impose a national 3-day limit on opioid prescriptions following surgeries. He will be kind enough to allow exceptions for people dealing with cancer, chronic pain, and “other serious matters”—whatever that means....
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
A study published last month in the peer-reviewed journal  Addiction by researchers at the British Columbia Centre for Disease Control and the British Columbia Centre on Substance Use found that harm reduction strategies were responsible for the province ’s opioid-related overdose death rate being less than half of what it otherwise would have been between April 2016 and December 2017.The researchers noted that 77 percent of opioid-related overdose deaths during that time frame involved illicit fentanyl. Vancouver has long been a major port of entry for fentanyl and fentanyl analogs, produced in China and o...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
Addiction is a chronic condition that leads to overdose and death. Addiction ruins lives, families and devastates communities. If you are suffering from addiction, it can be normal to ask yourself hard questions such as, “will I suffer from addiction forever? Is there a cure for addiction?” While there is no magic wand that can cure addiction, it is a treatable condition. When addiction is treated, people can go on to live normal, happy, healthy lives. While addiction may cause a lot of destruction and fractured relationships in its path, people can repair and move on from them as well. The Cure for Addiction:...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction Recovery Complementary Therapies Comprehensive behavioral treatment Healthy Eating and Recovery Mental Health Sober Living and Aftercare Substance Abuse addicted to alcohol addiction help addiction recovery programs Source Type: blogs
You're reading The Impact of the Media’s Glamorization of Drug Abuse on Mental Health, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. We often hear about celebrities with addictions from various news outlets. Addiction and mental health issues can affect anyone. In fact, about 19% of all U.S. adults have dealt or are currently dealing with a mental illness, according to a national survey held by SAMHSA in 2017. The Role of Media in Drug Abuse It has been shown that the media contributes to the stigma of m...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: depression internet culture psychology self education self improvement celebrities with addictions celebrity overdoses role of media in drug abuse songs about drugs Source Type: blogs
Ready to Get Clean from Heroin and Opioids? Opioids are an extremely addictive medication, so it is no surprise that opioid addiction and overdoses are on the rise. As opioids become more expensive and difficult to obtain, many people turn to heroin in order to fulfill their needs. The more opioids someone takes, the more their body requires in order to feel the euphoric effects. This tolerance building can quickly snowball to dependency and eventual addiction. You probably realize that your heroin and opioid use is out of control and your body’s need for it is too great to handle alone. The only answer to stopping t...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction to Pharmaceuticals Drug Treatment Heroin Substance Abuse detox medical detox opiate opiate abuse opiate addiction opiates opioid opioids Source Type: blogs
Moira van Staaden* and Robert Huber* J.P. Scott Center for Neuroscience, Mind &Behavior, Bowling Green State University, Bowling Green, OH, United States Editorial on the Research Topic Invertebrate Models of Natural and Drug-Sensitive Reward The relationship between insects and humans is a complex one, characterized biotically as commensalism, mutualism, or parasitism. This collection of papers reveals yet another dimension, in which shared history invests invertebrate models with the power to interrogate critical challenges to the human reward system. As humans we take pride in approaching a gi...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
What is Clonidine? Originally developed as a nasal decongestant, Clonidine has been found to work very well for patients experiencing withdrawal symptoms from opiates. According to the JamaNetwork, Clonidine produces a rapid and statistically significant decrease in opiate withdrawal signs and symptoms. Clonidine administration for 14 days enabled all patients to be successfully detoxified from chronic opiate administration. In all patients studied, clonidine was a safe and effective non-opiate treatment of opiate withdrawal that suppressed the effect, signs, and symptoms of opiate withdrawal. Withdrawal Symptoms When some...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction Recovery Anxiety Detox Resources for Alcohol and Drugs/Opiates Drug Rehab Information Drug Treatment Substance Abuse drug detox medicated-assisted detox opiate abuse opiate addiction opioid opioids prescriptio Source Type: blogs
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