Gestational weight management and pregnancy outcomes among women of advanced maternal age.

In this study, we assessed the effects of pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on the pregnancy outcomes of women of advanced age using a back-propagation (BP) artificial neural network. We conducted a retrospective analysis on postpartum and hospital delivery data from 1,015 women of advanced maternal age (AMA) hospitalized at the Fujian Provincial Maternity and Children's Hospital from January to June, 2017. Pre-pregnancy overweight was found to increase the incidence of gestational diabetes mellitus (GDM), hypertensive disorders complicating pregnancy (HDCP) and fetal macrosomia. In addition, poor weight gain during pregnancy increased the chances of pre-term births (PTBs). Furthermore, excessive weight gain during pregnancy increased the incidence of macrosomia in women of AMA. On the whole, the findings of this study suggest that controlling the pre-pregnancy BMI and the GWG may reduce the incidence of adverse pregnancy outcomes in women of AMA. The BP neural network is suitable for the study of weight changes in this population. PMID: 31410130 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research

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This study included 57 patients, who had been diagnosed as having GDM at their 24-28th gestational week, and 29 controls. The maternal blood samples were collected at the 24-28th gestational week and ADAMTS5 was studied with the enzyme-linked immunosorbent assay (ELISA) method, whereas an automated colorimetric method was used to study TAS, TOS, and OSI. The level of ADAMTS5 in maternal serum of patients with GDM were significantly lower than the controls (p = .017); whereas TOS and OSI levels were significantly higher (p = .003 and p = .008). Multivariable logistic regression anal...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
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Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
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Source: Journal of the Academy of Nutrition and Dietetics - Category: Nutrition Source Type: research
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Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research
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Source: Asia Pacific Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Asia Pac J Clin Nutr Source Type: research
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Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Mechanisms, Equipment, Hazards Source Type: research
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Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Mother, Fetus, Neonate Source Type: research
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Source: Diabetology and Metabolic Syndrome - Category: Endocrinology Authors: Tags: Review Source Type: research
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Source: Diabetology and Metabolic Syndrome - Category: Endocrinology Authors: Tags: Research Source Type: research
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Source: Endocrine - Category: Endocrinology Source Type: research
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