The Lipid Paradox Among Acute Ischemic Stroke Patients-A Retrospective Study of Outcomes and Complications.
CONCLUSIONS: In 2014, there were 28,212,820 (2.02% AIS and 5.50% LDs) hospitalizations. LDs patients had higher prevalence and odds of having AIS compared with non-LDs. Between 2003-2014, of the total 4,224,924 AIS hospitalizations, 451,645 (10.69%) had LDs. Patients with LDs had lower percentages and odds of mortality, risk of death, major/extreme disability, discharge to nursing facility, and complications including epilepsy, stroke-associated pneumonia, GI-bleeding and hemorrhagic-transformation compared to non-LDs. Although LDs are risk factors for AIS, concurrent LDs in AIS is not only associated with lower mortality and disability but also lower post-stroke complications and higher chance of discharge to home. PMID: 31412670 [PubMed - in process]
Publication date: Available online 21 January 2020Source: The American Journal of SurgeryAuthor(s): Andrea Gillis, Ashley Pfaff, Ashar Ata, Alexa Giammarino, Steven Stain, Marcel TafenAbstractBackgroundIt is unclear what drives variation in timing to tracheostomy among different patients.MethodsAge, ethnicity, admission service, and income were retrospectively collected for patients undergoing tracheostomy in a level 1 trauma center from 2007 to 2017. The primary outcome was time to tracheostomy with early tracheostomy (ET) or late tracheotomy (LT) defined as 3–7 or ≥ 10 days post-intubation, respectively. Sec...
Publication date: Available online 22 January 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Giuseppe De Luca, Monica Verdoia, Stefano Savonitto, Luca A. Ferri, Luigi Piatti, Daniele Grosseto, Nuccia Morici, Irene Bossi, Paolo Sganzerla, Giovanni Tortorella, Michele Cacucci, Maurizio Ferrario, Ernesto Murena, Girolamo Sibilio, Stefano Tondi, Anna Toso, Sergio Bongioanni, Amelia Ravera, Elena Corrada, Matteo MarianiAbstractBackgroundElderly patients are at increased risk of hemorrhagic and thrombotic complications after an acute coronary syndrome (ACS). Frailty, comorbilities and low body weight hav...
ConclusionThis study demonstrated that a good quality of life was observed among the majority of CWE and their caregivers, although some factors such as a male caregiver gender and lower level of education were associated with poor QoL.
Publication date: Available online 21 January 2020Source: SeizureAuthor(s): Petra Redfors, Lukas Holmegaard, Annie Pedersen, Christina Jern, Kristina MalmgrenAbstractPurposeTo assess long-term incidence and predictors of post-stroke epilepsy (PSE) and to evaluate the antiepileptic drug (AED) treatment in a well characterized cohort of middle-aged patients.MethodsThe study is based on the Sahlgrenska Study on Ischemic stroke, and included 1066 adult patients with first-ever or recurrent acute ischemic stroke (AIS) before the age of 70. Early seizures (ES) were defined as seizures within one week and PSE as unprovoked seizur...
ConclusionsExpression of SSTRs and activation of mTOR pathway in paediatric glioneuronal tumour suggest that somatostatin analogues and mTOR inhibitors may have potential therapeutic implications in a subset of inoperable childhood glioneuronal tumours causing medically refractory epilepsy and/or tumour growth. Further clinical studies are warranted to validate these findings.
ConclusionComorbidity increased the rate of all-cause, but not MS-specific, hospital admissions. Hospitalization rates were higher during the earlier stages of MS. Therefore, recognizing and managing comorbidity in the MS population, especially early in the disease course, will likely have the biggest impact on reducing overall hospital admissions.
JAMES MOORE is the actor famed for playing the role of Ryan Stocks in the popular show Emmerdale. James revealed a disability he suffers from. What is it and what are the symptoms?
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TC-325 (Hemospray, Cook Medical, Winston-Salem, North Carolina, USA) is a propriety mineral blend powder developed for the purpose of endoscopic hemostasis. The powder was originally approved for use in stopping bleeding from external wounds in both civilian and military injuries. In 2011, our group reported its first endoscopic application in patients with actively bleeding peptic ulcers.1 The powder was sprayed onto the bleeding vessel with the use of a pressurized carbon dioxide canister. In 19 of 20 patients, hemostasis was achieved.