Platelet-rich plasma in treatment of patients with idiopathic carpal tunnel syndrome

ConclusionPlatelet-rich plasma could be effective treatment of mild to moderate idiopathic CTS and superior to corticosteroid in improving pain, function, and distal sensory latency of median nerve.Trial registrationClinicalTrials.gov Identifier: NCT03863873Key Points:•PRP is effective treatment of mild to moderate CTS.•PRP is superior to corticosteroids in improving pain and function in CTS.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research

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AbstractIntroductionWe compared the preoperative quality of life (QOL) of patients with carpal tunnel syndrome, lower extremity-, and para-lumbar entrapment syndrome, and the effect of surgery on their QOL.Patients and methodsWe prospectively enrolled 66 consecutive patients who underwent surgery for carpal tunnel syndrome (group 1,n = 23), lower extremity entrapment syndrome (group 2,n = 22), and para-lumbar entrapment syndrome (group 3,n = 21). Their pre- and postoperative overall health status was assessed on the Medical Outcomes Study Short-Form 36 Health Survey, v2 (SF-36).Res...
Source: Acta Neurochirurgica - Category: Neurosurgery Source Type: research
Carpal tunnel syndrome is a common upper-limb nerve compression disease. Carpal tunnel syndrome can lead to several symptoms such as tingling or numbness, pain in the hand or wrist, and reduced grip strength. ...
Source: BMC Musculoskeletal Disorders - Category: Orthopaedics Authors: Tags: Research article Source Type: research
THURSDAY, Jan. 16, 2020 -- From carpal tunnel to a stiff neck, too much time on the computer can cause a slew of health problems. But what if you ditch the keyboard and mouse for virtual reality? New research from Oregon State University in...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Authors: Gudin J, Nalamachu S Abstract Interest in and use of topical analgesics has been increasing, presumably due to their potential utility for relief of acute and chronic pain. Topically applied agents with analgesic properties can target peripheral nociceptive pathways while minimizing absorption into the plasma that leads to potential systemic adverse effects.Clinical trials have found 5% lidocaine patches to be effective and well tolerated for the treatment of post-herpetic neuralgia (PHN) with a minimal risk of toxicity or drug-drug interactions. With this patch formulation, the penetration of lidocaine in...
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Conclusions: Even though both MNCSA and MNT were significantly associated with CTS, MNT was identified as a more suitable measurement parameter. PMID: 31888318 [PubMed]
Source: Korean Journal of Pain - Category: Anesthesiology Tags: Korean J Pain Source Type: research
Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
Conditions:   Chronic Pain;   Carpal Tunnel Syndrome Interventions:   Device: transcranial Direct Current Stimulation (tDCS);   Device: Transcranial Ultrasound (TUS) Sponsors:   Spaulding Rehabilitation Hospital;   Highland Instruments, Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ObjectivePerineural injection with 5% dextrose (D5W) is a novel strategy in the treatment of carpal tunnel syndrome (CTS). In contrast, perineural injection with corticosteroid has been used for decades for treating CTS, but possible neurotoxicity has been a major concern. No studies investigating the comparative effects have been published so far. The authors performed a prospective, randomized, double ‐blinded, head‐to‐head comparative trial to compare these two approaches for patients having mild‐to‐moderate CTS.MethodsFifty ‐four participants with mild‐to‐moderate CTS were randomly divided into dextrose...
Source: Annals of Neurology - Category: Neurology Authors: Tags: Research Article Source Type: research
Publication date: Available online 5 July 2017 Source:Journal of Clinical Neuroscience Author(s): Ying-Chen Kuo, Chia-Cheng Lee, Lin-Fen Hsieh Carpal tunnel syndrome (CTS) is a common and sometimes challenging condition, which causes pain; paresthesia; tingling of the thumb, index and long fingers; and even thenar weakness in the hands. The effectiveness of corticosteroid injections seems to be transient, and there is a lack of information around long-term effects in previous studies. In recent years, platelet-rich plasma (PRP) has proven to bean alternative as it encourages tissue regeneration. We hereby describe a patie...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Abstract Carpal tunnel syndrome, the most common entrapment neuropathy of the upper extremity, is caused by compression of the median nerve as it travels through the carpal tunnel. Classically, patients with the condition experience pain and paresthesias in the distribution of the median nerve, which includes the palmar aspect of the thumb, index and middle fingers, and radial half of the ring finger. Additional clues include positive physical examination findings, such as the flick sign, Phalen maneuver, and median nerve compression test. Although patients with typical symptoms and signs of carpal tunnel syndrome...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
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