Disparities in access to best stroke treatment

(Reuters Health) - Less than 10% of U.S. stroke patients get a treatment that evidence shows is most effective for a certain type of stroke – and the odds are even lower for patients who are black and Hispanic, a U.S. study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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People genetically predisposed to sleep problems have greater risk of stroke and coronary artery diseasePeople who struggle with sleep might be at greater risk of developing cardiovascular problems, research suggests.Scientists have found that people who are genetically predisposed to insomnia have a greater risk of heart failure, stroke and coronary artery disease.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Sleep Health & wellbeing Life and style Science Heart disease Stroke UK news Society Source Type: news
Source: Neuropsychiatric Disease and Treatment - Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research
Publication date: Available online 17 August 2019Source: The Annals of Thoracic SurgeryAuthor(s): Niv Ad, Sari D. Holmes, Harold G. Roberts, J. Scott Rankin, Vinay BadhwarAbstractBackgroundSurgical treatment of symptomatic atrial fibrillation (AF) has been performed for three decades. We reviewed trends and outcomes of surgical ablation (SA) for stand-alone AF using the Society of Thoracic Surgeons Adult Cardiac Surgical Database (STS-ACSD).MethodsThe STS-ACSD was reviewed from 2011-2017 (N=7,187) for trends. Contemporary data from 2014-2017 (N=3,893) were used to compare three subgroups: off-pump (n=3,252), on-pump (n=491...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
The zymogen form of circulating Factor VII activating protease (FSAP) is activated by histones that are released as a consequence of tissue damage or excessive inflammation. This is likely to have consequences in a number of disease conditions such as stroke, atherosclerosis, liver fibrosis, thrombosis and cancer. To investigate the existence, as well as the concentration, of active FSAP (FSAPa) in complex biological systems an active site probe is needed. We used Hybrid Combinatorial Substrate Library (HyCoSuL) to screen for natural and unnatural amino acids that specifically bind to P4-P2 pockets of FSAPa.
Source: Thrombosis Research - Category: Hematology Authors: Tags: Full Length Article Source Type: research
AbstractSwallowing is a complicated, multilevel and neuromuscular physiological function. Transcutaneous neuromuscular electrical stimulation is a relatively new therapeutic intervention for the treatment of swallowing disorders. The aim was to administer and focus on pre and post therapy effects of traditional dysphagia therapy and electrical stimulation (TENS) in 2 participants with posterior stroke. Electrical current along with traditional dysphagia therapy on regular intervals with adequate current levels post stroke. These cumulative therapeutic strategies helped in improving the swallowing mechanism. TENS is one of ...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research
Publication date: Available online 10 August 2019Source: Annals of Physical and Rehabilitation MedicineAuthor(s): M. Compagnat, S. Mandigout, C.S. Batcho, N. Vuillerme, J.Y. Salle, R. David, J.C. DavietAbstractBackgroundRecent studies reported that wearable sensor devices show low validity for assessing the amount of energy expenditure in individuals after stroke.ObjectiveWe aimed to evaluate the validity of energy expenditure calculation based on the product of energy cost and walked distance estimated by wearable devices in individuals after hemispheric stroke.MethodsWe recruited individuals with hemispheric stroke seque...
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
ConclusionThe incidence of early poststroke seizures was overall rare, and no significant differences emerged between patients receiving and those not receiving reperfusion therapies.This article is part of the Special Issue “Seizures and Stroke”.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Publication date: Available online 17 August 2019Source: Journal of Clinical NeuroscienceAuthor(s): Julius Griauzde, Vijay M. Ravindra, Neeraj Chaudhary, Joseph J. Gemmete, Aditya S. PandeyAbstractMechanical thrombectomy is now at the forefront of the treatment of large vessel acute ischemic stroke (AIS). Selective intra-arterial (IA) access has opened a new avenue for neuroprotection in AIS that has the potential to maximize local benefit while minimizing systemic effects. On a cellular level, neuroprotective strategies are aimed at reducing inflammation and free-radical formation, maintaining blood-brain barrier fidelity...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Contributors : Tadashi Sunohara ; Asuka MorizaneSeries Type : Non-coding RNA profiling by arrayOrganism :Cell-based therapy is a promising treatment for neurodegenerative diseases such as Parkinson ’s disease or cardiac disease. Similarly, reconstruction of the corticospinal tract by cell transplantation is expected as a treatment for stroke and degenerative disease. For efficient cell integration to the corticospinal tract after transplantation, the induction or selection of corticofugal projection neuron (CFuPN) is important. However, no CFuPN specific surface markers for the purification are known. Recently, miRN...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Source Type: research
In conclusion, our data show how oncogenic and tumor-suppressive drivers of cellular senescence act to regulate surveillance processes that can be circumvented to enable SnCs to elude immune recognition but can be reversed by cell surface-targeted interventions to purge the SnCs that persist in vitro and in patients. Since eliminating SnCs can prevent tumor progression, delay the onset of degenerative diseases, and restore fitness; since NKG2D-Ls are not widely expressed in healthy human tissues and NKG2D-L shedding is an evasion mechanism also employed by tumor cells; and since increasing numbers of B cells express NKG2D ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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