Previous dengue or Zika virus exposure can drive to infection enhancement or neutralisation of other flaviviruses.

CONCLUSIONS: The co-circulation of those viruses in the same area represents a risk for the development of severe infections if they spread throughout the country. Successive flavivirus infections may have an impact on disease pathogenesis, as well as on the development of safe vaccine strategies.
PMID: 31411310 [PubMed - in process]

Source: Memorias do Instituto Oswaldo Cruz - August 16, 2019 Category: Infectious Diseases Authors: Oliveira RA, de Oliveira-Filho EF, Fernandes AI, Brito CA, Marques ET, Tenório MC, Gil LH Tags: Mem Inst Oswaldo Cruz Source Type: research