Clinical characteristics and treatment outcomes of Enterococcus durans bacteremia: a 20-year experience in a tertiary care hospital

AbstractWhile the clinical characteristics and treatment outcomes ofEnterococcus faecalis andE. faecium bacteremia are well known, those ofE. durans bacteremia are still largely unclear. We retrospectively identified 80 adultE. durans bacteremia cases treated at our 2700-bed tertiary care hospital between January 1997 and December 2016. We compared the clinical characteristics and treatment outcomes of the adult patients withE. durans bacteremia (case group) with those ofE. faecalis andE. faecium bacteremia cases (two control groups). The case and control groups were matched for sex, age, and date of onset of bacteremia.E. durans was responsible for 1.2% of all enterococcal bacteremia cases at our hospital. Of 80 cases, 39 (48.8%) had biliary tract infection and 18 (22.5%) had urinary tract infection. Community-onset bacteremia was more frequent in the case group than in the control groups (56.2% vs. 35.0% vs. 21.2%,p 
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research

Related Links:

This study examined imported frozen poultry products for antibiotic residues considering their health implications. A solid-phase extraction method using liquid chromatography-tandem mass spectrometry in the positive and negative electrospray ionisation and the multiple reaction monitoring modes were employed. The antibiotics were extracted with acetonitrile-dichloromethane. Chromatographic separation was on Waters Acquity UPLC® BEH C18 column with acetonitrile, and water gradient and the antibiotics analysed using Electrospray positive ionisation polarity switch in a single run of fourteen minutes. Residues of ninetee...
Source: Toxicology Reports - Category: Toxicology Source Type: research
In this study, we compared antibacterial activity of CaOH-ZO pastes using different mixture ratios sagainst Enterococcus faecalis as an important bacterium in root canal treatment failure. Materials and Methods: Seven types of pastes were prepared in our laboratory. The first group included one gram of ZO+eugenol, second group included one gram of CaOH+distilled water, third group included 0.5gram ZO+0.5gram CaOH+distilled water (1:1), forth group included 0.75gramCaOH+0.25gramZO+distilled water (3:1), the fifth group included 0.33gram of CaOH+0.66gram of ZO+distilled water (1:2), the sixth group included 0.75gram of Z...
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
Publication date: 2019Source: European Urology Supplements, Volume 18, Issue 5Author(s): S.M. Croghan, J. O’Donovan, T. McBride, C. Albu, J.S.A. Khan, D. McNicholas, S. David, N. Nabi, G. Nama, T. Jacob, H.D. Flood, S.K. Giri
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research
In this study, the effects of COS on colorectal cancer (CRC) development were evaluated using azoxymethane and dextran sulfate sodium (AOM/DSS) induced mouse model of CRC (CACM). In the COS-treated CRC group (CMCOS), COS protected mice from CRC by decreasing the disease activity index, tumor incidences and multiplicity, and the mRNA levels of COX-2, IL-6, TNF-α, IL-1β, IL-10, and IKK-β mRNA in colonic epithelial cells. The results of a cage-exchanged experiment, in which mice from the CACMe and CMCOSe treatments exchanged cages every day to interact with microbes, showed that gut microbes play an important ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion: Bactericidal parameters of ready-to-use disinfectant wipes should be determined in surface tests, in addition to suspension tests, because suspension tests do not simulate the conditions under which disinfectant wipes are used in practice.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Introduction: Hospitalized patients with urinary tract infections (UTIs) often present with comorbid illnesses and are subsequently prescribed multiple medications, which increases the likelihood of drug-drug interactions. Therefore, this study aimed to explore the prevalence, levels, risk factors, and clinical relevance of potential drug-drug interactions (pDDIs) in hospitalized patients with UTIs. Secondly, we aimed to develop management guidelines and identify monitoring parameters for the most frequent interactions.Methods: A retrospective cross-sectional study was conducted in internal medicine wards of two tertiary c...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Hamat Enterococci are commonly found in humans, animals and environments. Their highly adaptive mechanisms are related to several virulent determinants and their ability to resist antibiotics. Data on the relationship between the esp gene, biofilm formation and antibiotic susceptibility profiles may differ between countries. This cross-sectional study was conducted to determine the proportion of esp gene and biofilm formation among Enterococcus faecalis and Enterococcus faecium clinical isolates. We also investigated the possible association between the esp gene with antibiotic susceptibility patterns and biofilm forma...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Amer J Perinatol DOI: 10.1055/s-0039-1696721 Objective Our primary objective was to identify risk factors for maternal readmission with sepsis. Our secondary objectives were to (1) assess diagnoses and infecting organisms at readmission and (2) compare early (
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: SMFM Fellowship Series Article Source Type: research
We present a case of an 85 years old male with history of valvular disease and permanent pace maker with past medical history of repetitive urinary tract infections in the previous months, who presented to the emergency department with fever, urinary disturbances, general malaise and positive blood cultures for Enterococcus Gallinarum. Echocardiography was a useful diagnostic method in the present case, showing the vegetation on the tricuspid valve. This case is notable because tricuspid valve endocarditis due to Enterococcus Gallinarum is a rare clinical condition and improves knowledge of disease and management in patien...
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
Enterococcus faecium is an important cause of hospital-associated infections, including urinary tract infections (UTIs), bacteremia, and infective endocarditis. Pili have been shown to play a role in the pathogenesis of Gram-positive bacteria, including E. faecium. We previously demonstrated that a nonpiliated empABC::cat derivative of E. faecium TX82 was attenuated in biofilm formation and in a UTI model. Here, we studied the contributions of the individual pilus subunits EmpA, EmpB, and EmpC to pilus architecture, biofilm formation, adherence to extracellular matrix (ECM) proteins, and infection. We identified EmpA as th...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Molecular Pathogenesis Source Type: research
More News: Endocarditis | Enterococcus | Hospitals | Infectious Diseases | Infective Endocarditis | Microbiology | Penicillin | Urinary Tract Infections