The protective role of l -carnitine against 1st- and 2nd-generation antihistamine-induced liver injury in mice

In conclusion, oxidative stress can be a possible explanation of hepatic damage induced by chronic therapy with chlorpheniramine maleate and cetirizine hydrochloride.l-Carnitine has prominent hepatoprotective effects on chlorpheniramine maleate – and cetirizine hydrochloride–induced hepatic damage possibly through improvement of hepatic function and decreasing oxidative stress.
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research