The Efficacy of Group Cognitive-Behavioral Therapy plus Duloxetine for Generalized Anxiety Disorder Versus Duloxetine Alone.

The Efficacy of Group Cognitive-Behavioral Therapy plus Duloxetine for Generalized Anxiety Disorder Versus Duloxetine Alone. Acta Neuropsychiatr. 2019 Aug 13;:1-14 Authors: Xie ZJ, Han N, Law S, Li ZW, Chen SY, Xiao JP, Zhang Y, Gao BL, Jiang SS, Gao HM, Huang XB Abstract OBJECTIVE: To explore whether and how group cognitive-behavioural therapy (GCBT) plus medication differs from medication alone for the treatment of generalized anxiety disorder (GAD). METHODS: 170 patients were randomly assigned to the GCBT plus duloxetine (n=89) or duloxetine group (n=81). The primary outcomes were Hamilton Anxiety Scale (HAMA) response and remission rates. The explorative secondary measures included score reductions from baseline in the HAMA total, psychic and somatic anxiety subscales (HAMA-PA, HAMA-SA), the Hamilton Depression Scale (HAMD), the Severity Subscale of Clinical Global Impression Scale (CGI-S), Global Assessment Function (GAF), and the 12-item Short-Form Health Survey (SF-12). Assessments were conducted at baseline, 4-weeks, 8-weeks and 3-monthsfollow-up. RESULTS: At 4-weeks, HAMA response (GCBT group 57.0% vs. control group 24.4%, p=0.000, Cohen d=0.90) and remission rates (GCBT group 21.5%vs. control group 6.2%, p=0.004; d=0.51), and most secondary outcomes (all p
Source: Acta Neuropsychiatrica - Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

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Publication date: Available online 10 August 2019Source: Obesity Research &Clinical PracticeAuthor(s): Sanjeev Sockalingam, Samantha E. Leung, Raed Hawa, Susan Wnuk, Sagar V. Parikh, Timothy Jackson, Stephanie E. CassinAbstractObjectiveAlthough bariatric surgery is a durable treatment for patients with severe obesity, it does not directly address behavioural and psychological factors that potentially contribute to weight regain post-surgery. Psychological interventions, such as cognitive behavioural therapy (CBT), can be challenging to access due to physical limitations and practical barriers. Telephone-based CBT (Tele...
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
DiscussionOur systematic approach combined rigour and transparency to develop a therapeutic intervention tailored to the specific needs of older adults with treatment-resistant GAD.
Source: Age and Ageing - Category: Geriatrics Source Type: research
ConclusionReassurance seeking appears to be a common factor across anxiety disorders though the themes of the reassurance may differ. Further, reduction in excessive reassurance seeking may be an important component in treatment outcome.
Source: Journal of Anxiety Disorders - Category: Psychiatry Source Type: research
Conclusion: This is the first implementation of SocialMind, which is the first mindfulness-based social cognition training. It is well tolerated by participants with schizophrenia spectrum disorders, and a further randomized controlled trial is proposed for people who have suffered their first episode of psychosis within the past 5 years.Clinical Trial Registration:, identifier NCT03434405.IntroductionPeople suffering from psychosis frequently find it difficult to establish or maintain relationships with others or to engage in community activities (1, 2). These deficits are present even in high-risk ...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusions: Compared with waiting list, guided iCBT is effective and likely results in symptom improvement in mild to moderate major depression and social phobia. Guided iCBT may improve the symptoms of generalized anxiety disorder and panic disorder compared with waiting list. However, we are uncertain about the effectiveness of iCBT compared with individual or group face-to-face CBT. Guided iCBT represents good value for money and could be offered for the short-term treatment of adults with mild to moderate major depression or anxiety disorders. Most people with mild to moderate depression or anxiety disorders with whom...
Source: Ontario Health Technology Assessment Series - Category: General Medicine Tags: Ont Health Technol Assess Ser Source Type: research
This study supports existing research showing promise for the application of rt-fMRI neurofeedback in the treatment of problems like PTSD, addiction and depression that are associated with heightened amygdala activation. The clinical potential of this technique, bridging the worlds of neurobiology and psychotherapy, is clear. That said, fMRI scanning is an expensive business, so it may be a while before a new world of personalised mental health interventions reveals itself. —Training emotion regulation through real-time fMRI neurofeedback of amygdala activity Post written by Eleanor Morgan (@eleanormorgan) for B...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Brain guest blogger Mental health Source Type: blogs
y M Abstract Atopic dermatitis (AD) is a common and debilitating inflammatory dermatological disorder and is marked by itch and inflamed skin. Scratching, sleep loss, and avoidance of situations associated with more AD symptoms are central hypothesized mechanisms that perpetuate the disorder and cause reduced quality of life. We developed an exposure-based cognitive behavioral treatment (CBT) that entailed mindfulness practice as a means to increase tolerance for aversive experiences during exposure. The aim of the present study was to test the treatment's acceptability and preliminary efficacy in adults with AD. ...
Source: Cognitive Behaviour Therapy - Category: Psychiatry & Psychology Authors: Tags: Cogn Behav Ther Source Type: research
AbstractBackgroundWe aimed to evaluate the acceptability and efficacy of two brief, Internet-delivered cognitive behavioural therapy interventions —MUMentum Pregnancy (study 1) andMUMentum Postnatal (study 2) —in reducing maternal symptoms of anxiety, depression and overall psychological distress compared to usual care in the perinatal period.Methods/DesignWomen who are pregnant (study 1) or  
Source: Trials - Category: Research Source Type: clinical trials
Conclusions: Compared with usual care, treatment with CBT, interpersonal therapy, or supportive therapy significantly reduces depression symptoms posttreatment. CBT significantly reduces anxiety symptoms posttreatment in patients with generalized anxiety disorder.Compared with usual care, treatment with structured psychotherapy (CBT or interpersonal therapy) represents good value for money for adults with major depressive disorder and/or generalized anxiety disorder. The most affordable option is group structured psychotherapy provided by nonphysicians, with the selective use of individual structured psychotherapy provided...
Source: Ontario Health Technology Assessment Series - Category: General Medicine Tags: Ont Health Technol Assess Ser Source Type: research
Conclusions Telephone facilitation of cCBT improves engagement and expedites depression improvement. The effect was small to moderate and comparable with other low-intensity psychological interventions.
Source: The British Journal of Psychiatry - Category: Psychiatry Authors: Tags: PAPERS Source Type: research
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