Association of Oral Lichen Planus and Thyroid Gland Diseases Association of Oral Lichen Planus and Thyroid Gland Diseases
This study investigated a possible link between these two immune-related conditions.BMC Oral Health
AbstractSelective immunoglobulin A deficiency (SIgAD) is the most common primary immunodeficiency, defined as an isolated deficiency of IgA (less than 0.07 g/L). Although the majority of people born with IgA deficiency lead normal lives without significant pathology, there is nonetheless a significant association of IgA deficiency with mucosal infection, increased risks of atopic disease, and a higher prevalence of autoimmune disease. To explain thes e phenomena, we have performed an extensive literature review to define the geoepidemiology of IgA deficiency and particularly the relative risks for developing systemic...
This study aimed to evaluate the immunohistochemical expression of thyroid-stimulating hormone (TSH) and thyroid-stimulating hormone receptor (TSHR) in healthy oral mucosa and in OLP lesions of individuals with and without HT.
ConclusionsA significant number of patients with OLP who are not previously diagnosed with thyroid disease have thyroid parameters that are compatible with hypothyroidism. The expression of thyroid‐stimulating hormone receptor in OLP lesions suggests that mechanisms related to autoimmune thyroid disease are involved in the aetiology of OLP.This article is protected by copyright. All rights reserved.
Koilonychia is a common concave nail dystrophy in which the nail plate is depressed centrally and elevated laterally.1 The term has Greek origins, with koilos meaning spoon. The pathophysiology of koilonychia, or spoon nails, is poorly understood. It has been associated with dermatologic disorders such as alopecia areata, psoriasis, and lichen planus; endocrinopathies such as hypothyroidism, hyperthyroidism, and diabetes mellitus; nutritional deficiencies, notably iron deficiency anemia; genodermatoses; and traumatic and occupational exposures.
CONCLUSION: Epicutaneous patch testing disclosed a high proportion of relevant positives. This guided the clinical decision to change dental restorations, with high rate of clinical improvement. PMID: 28695565 [PubMed - as supplied by publisher]
ConclusionEpicutaneous patch testing disclosed a high proportion of relevant positives. This guided the clinical decision to change dental restorations, with high rate of clinical improvement.
Conclusion: The general dental provider should be familiar with mucous membrane pemphigoid and the potential association with hypothyroidism. Early diagnosis of hypothyroidism is significant because replacement may prevent a significant morbidity associated with this condition. Therefore, the general dental provider should be aware of oral conditions presented as desquamative gingivitis and their potential association with hypothyroidism.
A 48-year-old Indian female with hypothyroidism, hypertension, and GERD presented with asymptomatic brown to black macules, some coalescing into a patch, located peri-orbitally, on the malar cheeks, and on the anterolateral neck bilaterally. No active red border was appreciated, and no lesions were noted on the palms, soles, nails, or mucous membrane. Lesions had been present for several months. She reported a history of pruritus and scaling however denied any pain or prior redness. Patient did observe darkening of pigmentation on exposure to sunlight.
Abstract A 77-year-old woman born in the Dominican Republic presented with fullness of the glabella and medial eyebrows for 1 year followed by alopecia of the lateral eyebrows and frontal hairline. She stated that although she had a high hairline at baseline, it had receded in the past year. She had also noted central scalp hair thinning that started 6 years earlier. She denied all styling practices that used traction or chemical processes, although she admitted to hair dye and blow dryer use. She reported "acne" in the central face for decades and darkening of the skin on the lateral face for several ye...
Conclusions: In the present study, OLP patients were associated with thyroid disease, specifically with hypothyroidism. Because most thyroid patients need T4 treatment, our findings confirmed that OLP and thyroid disease could be comorbidities.Dermatology