Research on mechanism of charred hawthorn on digestive through modulating “brain-gut” axis and gut flora

ConclusionThe above study showed that hawthorn decoction coupled with the odor of charred hawthorn effectively alleviate HC-DID in rats by regulating the “Brain-Gut” axis and gut flora. Odor treatment of hawthorn could be a potential therapeutic approach for HC-DID.Graphical abstractTraditional Chinese medicine decoction of hawthorn (raw hawthorn and charred hawthorn) regulated the body weight, food intake, gastrointestinal motility and abnormal secretion of brain-gut peptides in rats with high-calorie-diet-induced dyspepsia, and the odor of charred hawthorn also had good curative effect for it. Moreover, the intestinal dysbiosis was induced by high-calorie diet in rats with dyspepsia, and hawthorn decoction could ease this trend.
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research