Large animal models of Huntington's disease offer new and promising research options

(IOS Press) Scientific progress in HD relies upon availability of appropriate animal models enabling insights into genetics and/or pathophysiology. Large animal models, like domesticated farm animals, offer some distinct advantages over rodents, including a larger brain amenable to imaging and intracerebral therapy, longer lifespan, and more human-like neuro-architecture. Three articles in the latest issue of the Journal of Huntington's Disease discuss the potential benefits of using large animal models in HD research and the implications for the development of gene therapy.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news