CF3COOH/O2-Mediated Metal-Free Domino Construction of the Isatin Skeleton

Synlett DOI: 10.1055/s-0039-1690018 Directed by the strategy of C–H activation, an efficient construction of the isatin skeleton was developed through aerobic oxidation of glycine esters. The reactions were performed under CF3COOH/O2 conditions in the absence of metal catalysts. The reaction mechanisms were investigated with control experiments. [...] © Georg Thieme Verlag Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Synlett - Category: Chemistry Authors: Tags: letter Source Type: research
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