SUN-PO078: Home Parenteral Nutrition in Advanced Ovarian Cancer: Making and Implementing the Decision

Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Nutrition and cancer I Source Type: research

Related Links:

Discussion MDSCs violently emerge in pathological conditions in an attempt to limit potentially harmful immune and inflammatory responses. Mechanisms supporting their expansion and survival are deeply investigated in cancer, in the perspective to reactivate specific antitumor responses and prevent their contribution to disease evolution. These findings will likely contribute to improve the targeting of MDSCs in anticancer immunotherapies, either alone or in combination with immune checkpoint inhibitors. New evidence indicates that the expansion of myeloid cell differentiation in pathology is subject to fine-tuning, as its...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
We described our experience in the diagnosis and management of chylous ascites. Five hundred and forty-six patients were submitted to surgery for ovarian cancer and 298 patients received pelvic and/or para-aortic lymphadenectomy. Chylous ascites occurred in 8 patients with an incidence of 1.4% in the overall population and a 2.68% among patients receiving lymphadenectomy. All patients received total parenteral nutrition (TPN) with Olimel N4E 2000  mL (Baxter®) and somatostatin therapy with 0.2  mL per 3 times/day for a median of 9 days (range 7–11). Median hospital stay was 15 days (range 7&nd...
Source: Updates in Surgery - Category: Surgery Source Type: research
Conclusions and Perspectives In this review, we have discussed important milestones from the early description of “Serum-sickness” as being due to antibodies directed against Neu5Gc epitopes all the way to the present-day therapeutic implications of these antibodies in cancer therapy. Some of these milestones have been represented in a concise timeline (Figure 6). While the “Xenosialitis” hypothesis is well-supported in the human-like mouse models, it has yet to be conclusively proven in humans. It remains to be seen if “Xenosialitis” plays a role in other uniquely-human diseases. FI...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
This study investigated women ’s experiences on home PN as there is limited research in this area.
Source: Clinical Nutrition - Category: Nutrition Authors: Source Type: research
CONCLUSIONS: We are very uncertain whether HPN improves survival or quality of life in people with MBO as the certainty of evidence was very low for both outcomes. As the evidence base is limited and at high risk of bias, further higher-quality prospective studies are required. PMID: 30095168 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
by Drew RosielleTheAmerican Society of Clinical Oncology annual meeting, besides being a feast for the pharmaceutical business news pages (google'ASCO'and most of the hits will be about how announcement X affected drug company Y's stock), is also one of the premiere platforms for publishing original palliative-oncology research. So every year I try to at least scan the abstracts to see what's happening, and I figure I might as well blog about it. It's tough to analyze abstracts, so I'll mostly just be summarizing ones that I think will be of interest to hospice and palliative care folks. I imagine I've missed some good one...
Source: Pallimed: A Hospice and Palliative Medicine Blog - Category: Palliative Care Tags: artificial nutrition ASCO cannabanoid code status conference reviews fatigue hpmglobal marijuana mindfulness mucositis neuropathic oncology pain race rosielle scrambler Source Type: blogs
CONCLUSION: Nutritional decline and onset or deterioration of CAS are difficult to predict. Careful measuring and monitoring of nutritional parameters and CAS in all patients seems to be necessary in order to identify those patients in need of enteral/parenteral nutrition support. PMID: 29027398 [PubMed - in process]
Source: Journal of Gynecologic Oncology - Category: OBGYN Tags: J Gynecol Oncol Source Type: research
AbstractObjectivesTotal parenteral nutrition (TPN) presumably benefits cancer patients although reports have disputed the significance of this nutritional intervention. We sought to compare the postoperative outcomes of ovarian cancer patients treated with either TPN or conservative management.MethodsWe retrospectively evaluated the impact of TPN and conservative management in ovarian cancer patients who underwent debulking surgery and a bowel resection. The primary study variables encompassed patient time until restoration of bowel function, number of postoperative complications and duration of hospital stay.ResultsThere ...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Years of bowel disease and endometriosis had left me with a very sticky, complex pelvis. I reached the age of 50 and an MRI indicated I had ovarian cancer. This proved to be incorrect but my consultant was becoming increasingly concerned at the state of my insides and how the suspect masses presented on ultrasound and MRI’s. So much so he recommended a complete hysterectomy as otherwise I would live with this uncertainty for ever. This was four years ago – I was warned the surgery would be complex owing to numerous operations for bowel disease and endometriosis but on the basis the scans was no longer reliable,...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Your Stories endometriosis perforated bowel Source Type: news
More News: Cancer | Cancer & Oncology | Nutrition | Ovarian Cancer | Ovaries | Parenteral Nutrition