Gynecomastia in HIV-positive adult men receiving efavirenz-based antiretroviral therapy at Newlands clinic, Harare, Zimbabwe

We described the charac...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research

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We describe the clinical challenges of managing a 10-year-old boy who presented with repetitive episodes of torticollis. Open-mouth odontoid radiograph and computed tomographic (CT) scan gave a diagnosis in ARRS, based on its characteristic imaging findings. The child was admitted multiple times for continuous halter traction in the first 6 months after symptom onset. He also experienced a temporary complication from an overcorrection with correcting neck bracing. Seven months after symptom onset, this case was discussed by a multidisciplinary spine team and referred to chiropractic clinic. Despite persistent radiographic ...
Source: Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders - Category: Orthopaedics Tags: Clin Med Insights Arthritis Musculoskelet Disord Source Type: research
Background: Androgen receptor (AR) has been described to play a prominent role in male breast cancer (MBC). It maps on chromosome X, and recent reports indicate that X-chromosome polysomy is frequent in MBC. Since the response to anti-androgen therapy may depend on AR polysomy and on its overexpression similarly to prostate cancer, the aim of the present study was to investigate the DNA methylation level of AR and its coregulators, especially those mapped on the X-chromosome, that may influence the activity of AR in MBC.Methods: The DNA methylation level of AR, MAGEA2, MAGEA11, MAGEC1, MAGEC2, FLNA, HDAC6, and UXT, mapped ...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Conditions:   Gynecomastia;   Thoracic Interfascial Plane Block;   Thoracic Paravertebral Block;   Anesthesia Interventions:   Procedure: Tumescent local anesthesia;   Procedure: Thoracic paravertebral block;   Procedure: Thoracic interfascial plane block Sponsor:   Tanta University Recruiting
Source: - Category: Research Source Type: clinical trials
Source: Aesthetic Plastic Surgery - Category: Cosmetic Surgery Source Type: research
To investigate the feasibility of single-port endoscopic mastectomy via the lateral chest approach in the treatment of Simon grade II gynecomastia. Data from 12 patients with grade II gynecomastia admitted from January 2017 to November 2018 were retrospectively analyzed, and related satisfaction surveys were conducted 6 months after the operation. All surgeries were successfully performed under single-port endoscopy, and no patients were converted to open surgery. There were no serious complications related to the surgery, and all the patients were satisfied with the postoperative appearance. The application of single-p...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Quality Improvement Study Source Type: research
Publication date: Available online 11 May 2020Source: Academic RadiologyAuthor(s): Mohamad Ali Kazemi, Samira Hemmati, Behnaz Moradi, Hashem Sharifian, Kavous Firooznia, Nasrin Nikravangolsefid
Source: Academic Radiology - Category: Radiology Source Type: research
In this study, we describe two male siblings with mild intellectual disability, global developmental delay, short stature, microcephaly, and nyctalopia. Whole exome sequencing of the affected siblings and the parents identified a missense var iant (c.413C >  G) in thePHF6 gene, which leads to alteration of a serine residue at position 138 to cysteine. This mutation is located in a highly conserved region. Sanger sequencing confirmed the segregation of this mutation in the family in an X-linked recessive fashion. Multiple mass spectrometry-based proteomic studies have reported phosphorylation at serine 138 ...
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research
We report a case that occurred in the breasts of a 62-year-old man. A clinical diagnosis of gynecomastia was initially made. Partial mastectomy was done and MSL was reported on histopathologic examination. Our literature search revealed no previous case of MSL in the breast reported from our environment.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
Background: 47,XXY commonly known as Klinefelter syndrome (KS) is the most common male sex chromosome aneuploidy. The syndrome is characterized by hypotonicity, developmental delays, learning disabilities, and psychosocial problems during infancy/childhood and low testosterone production (hypogonadism) in adolesence/adulthood. Untreated, adolescents and adults may develop gynecomastia, osteoporosis and most commonly, infertility. The current standard of care offers treatment for KS at the onset of puberty for boys following molecular diagnosis.
Source: Journal of Pediatric Nursing - Category: Nursing Authors: Source Type: research
In conclusion, immunoglobulins exhibit limited benefit on immune ‐neuropathy in patients with coexisting KD.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
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