Cardiopulmonary exercise testing with ventilatory gas analysis for evaluation of chronic thromboembolic pulmonary hypertension: Unmasking its role after a therapeuthic intervention

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare but debilitating and life-threatening complication of acute pulmonary embolism (PE). CTEPH is defined as a mean pulmonary artery pressure (mPAP) of at least 25  mmHg at rest, caused by persistent obstruction of pulmonary arteries after PE that has not resolved despite at least 3 months of therapeutic anticoagulation [1]. CTEPH results from persistent obstruction of pulmonary arteries and progressive vascular remodeling [2,3]. Non-dissolution of thrombo embolic material may result in the formation of organized fibrotic scar tissue, webs and bands, which obstruct pulmonary arteries.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research