MiR-203a-3p inhibits retinal angiogenesis and alleviates proliferative diabetic retinopathy in oxygen-induced retinopathy (OIR) rat model via targeting VEGFA and HIF-1 α.

In conclusion, our findings demonstrate that up-regulation of miR-203a-3p might inhibit pathological retinal angiogenesis of PDR by targeting VEGFA and HIF-1α. PMID: 31408201 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31408201?dopt=Abstract

Source: Clinical and Experimental Pharmacology and Physiology - August 12, 2019 Category: Drugs & Pharmacology Authors: Han N, Xu H, Yu N, Wu Y, Yu L Tags: Clin Exp Pharmacol Physiol Source Type: research