TRPV1-mediated UCP2 upregulation ameliorates hyperglycemia-induced endothelial dysfunction

Conclusion: TRPV1 activation by capsaicin might protect against hyperglycemia-induced endothelial dysfunction through a mechanism involving the PKA/UCP2 pathway.

http://www.cardiab.com/content/12/1/69

Source: Cardiovascular Diabetology - April 22, 2013 Category: Cardiology Authors: Jing SunYunfei PuPeijian WangSijiao ChenYu ZhaoChan LiuQianhui ShangZhiming ZhuDaoyan Liu Source Type: research