Calcification biomarkers and vascular dysfunction in obesity and type 2 diabetes: influence of oral hypoglycemic agents.

In conclusion, obese patients with MUO/T2D have elevated circulating OPN, OPG and RANTES; in these patients, antidiabetic treatment reduces only circulating OPG. Further study is needed to better understand the mechanisms of vascular calcifications in obesity and diabetes.
PMID: 31408377 [PubMed - as supplied by publisher]

Source: Am J Physiol Endocri... - August 12, 2019 Category: Endocrinology Authors: Schinzari F, Tesauro M, Bertoli A, Valentini A, Veneziani A, Cambia U, Cardillo C Tags: Am J Physiol Endocrinol Metab Source Type: research