Invasive Fungal Infections in the Pediatric Intensive Care Unit

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Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: ESPID Reports and Reviews Source Type: research

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ConclusionsThe identification of the siderophore produced by Ilyonectria gives us further insight into the root rot disease that heavily affects ginseng crop yields. This research identifies a molecular pathway previously unknown for ginseng root rot and could lead to new disease treatment options.Graphical abstract
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research
AbstractsThe research explores the facile synthesis of some new phenylsulfamoyl carboxylic acids, their molecular docking, antimicrobial, and antioxidant activities. The procedure involved the mild reaction of amino acids with benzenesulfonyl chloride in a medium of aqueous base. The compounds were characterized using FTIR,1H-NMR,13C-NMR, and an elemental analysis. They were tested for their antimicrobial activities against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhi, Candida albicans, and Aspergillus niger microorganisms. The antioxidant activity of the compounds we...
Source: Medicinal Chemistry Research - Category: Chemistry Source Type: research
AbstractPurpose of ReviewThe purpose of this study is to provide an understanding of the increased range of patient cohorts at risk ofPneumocystis jirovecii pneumonia (PCP) and describe typical clinical presentations together with advances in diagnostic assays and strategies.Recent FindingsThe range of immuno-compromised patients at risk of PCP continues to expand. Apart from human immunodeficiency virus (HIV)-positive patients, those with solid tumours or suffering from haematological malignancy, solid organ transplant recipients or with autoimmune and inflammatory conditions receiving immuno-modulating therapies and pati...
Source: Current Fungal Infection Reports - Category: Infectious Diseases Source Type: research
The objective of this study was to test whether the change in pH in a liquid medium, colourimetrically established using the indicator phenol red, was linearly and directly proportional to the growth rate for Trichophyton rubrum and Trichophyton interdigitale. The changes in the colour determined by the phenol-red based assay showed a good correlation with the amount of fungal biomass over an incubation period of 24–120 h. The functionality of the phenol red assay was also validated in experiments on the growth of T. rubrum in the presence of antifungals. The changes in colour showed a clear dose-response relations...
Source: Journal of Microbiological Methods - Category: Microbiology Source Type: research
CONCLUSION: Our research proves that in Poland there is a problem of echinocandin resistance. Moreover, we identified two species of Candida which are rare causative agents of human infections, and there was no reported incidence of such infections in Poland until now. PMID: 31518088 [PubMed - as supplied by publisher]
Source: Acta Biochim Pol - Category: Biochemistry Authors: Tags: Acta Biochim Pol Source Type: research
Publication date: Available online 9 September 2019Source: Journal of American Association for Pediatric Ophthalmology and StrabismusAuthor(s): Allister S. Lee, Timothy J. SullivanAbstractPurposeTo report our experience in the diagnosis and management of invasive fungal infections with orbital involvement in children from a subtropical population.MethodsThe medical records of children (
Source: Journal of American Association for Pediatric Ophthalmology and Strabismus - Category: Opthalmology Source Type: research
CONCLUSION: Children with fever and SBS are at high risk for BSI with gram-positive and gram-negative organisms as well as fungus. WBC count at presentation is a poor predictor of BSI. Though elevated CRP increased the odds of BSI, its low negative predictive value made it a poor predictor of BSI in these patients. Children with SBS and fever should be treated urgently with broad-spectrum antibiotics. PMID: 31512263 [PubMed - as supplied by publisher]
Source: JPEN Journal Of Parenteral And Enteral Nutrition - Category: Nutrition Authors: Tags: JPEN J Parenter Enteral Nutr Source Type: research
Paras Ahmad, Usman Akhtar, Ahmed Chaudhry, Usman Rahid, Sarmad Saif, Jawaad Ahmed AsifEuropean Journal of General Dentistry 2019 8(3):55-62 Oral health is a cardinal element of nutritional as well as systemic well-being and plays a substantial part in sustaining optimum general health condition. Various factors influence oral health including metabolic diseases such as endocrine (diabetes mellitus [DM]), hematological, gastrointestinal, cutaneous, and neurological diseases. The intent of this review is to accentuate the correlation between DM and oral disorders, like those upsetting oral mucosa and supporting tissues. A r...
Source: European Journal of General Dentistry - Category: Dentistry Authors: Source Type: research
We report the case of a 16-year-old who presented after intentional ingestion of elemental iron (approximately 48 mg/kg). Iron levels at presentation were 4388 mcg/dl. The patient demonstrated symptoms of severe toxicity including hypotension, metabolic acidosis, and multiple organ failure. Fourteen days after ingestion, the patient suffered multiple punctate bowel perforations that were not related to ischemia and appeared to have been the result of local tissue injury from ingested iron. The bowel was successfully primarily repaired. However, the patient eventually succumbed due to the severity of multisystem organ fai...
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
To report our experience in the diagnosis and management of invasive fungal infections with orbital involvement in children from a subtropical population.
Source: Journal of AAPOS - Category: Opthalmology Authors: Tags: Major Article Source Type: research
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