Air-fluidized therapy in the treatment of severe burns: A retrospective study from a burn intensive care unit in Austria

Publication date: Available online 14 August 2019Source: BurnsAuthor(s): Stefanie Nickl, Alexandra Fochtmann-Frana, Jakob Nedomansky, Wolfgang Hitzl, Lars-Peter Kamolz, Werner HaslikAbstractIntroductionAir-fluidized therapy (AFT) has long been used in the treatment of severe burns. In patients with extensive burns involving the posterior trunk, we aim to keep affected posterior areas dry and to postpone their treatment, initially applying available split-thickness skin grafts in functionally more important regions. We retrospectively assessed the impact of AFT on the survival of patients treated in the burn intensive care unit (ICU) of the Medical University of Vienna, Austria, between 2003 and 2016.MethodsThis retrospective single-center study included patients aged ≥18 years with burned total body surface area (TBSA) ≥20% and IIb–III° thermal injuries on the posterior trunk who received AFT. Survival rates were compared with those predicted by the abbreviated burn severity index (ABSI). Demographic, clinical, and surgical data were analyzed.ResultsSeventy-five of 110 patients with posterior trunk burns received AFT. Their survival rate exceeded that predicted by the ABSI score (mean ABSI, 10.0 ± 2.0; 73.3% (95% CI: 62-83%) survival rate vs. 20-40% predicted; p 
Source: Burns - Category: Dermatology Source Type: research

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Pig skin isn ’t just for football these days.  Massachusetts General Hospital surgeons have successfully used genetically engineered pig skin for the temporary closure of a burn wound, the first time pig tissue derived from an animal with gene edits has been transplanted directly onto a human wound.  The F DA-cleared phase one clinical trial was led by surgeon Dr. Jeremy Goverman of MGH's Sumner Redstone Burn Center.  “It is not the trial itself that is so mind-boggling and intriguing to…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
Publication date: Available online 12 October 2019Source: BurnsAuthor(s): Julia Elrod, Dirk Moellmeier, Clemens Schiestl, Christoph Mohr, Kathrin NeuhausAbstractBackgroundOptimal management of palmar hand burns in children is controversial. We aimed to compare function and aesthetics of retroauricular full thickness skin grafts (FTSG) to plantar glabrous split thickness skin grafts (STSG).Methods32 palmar grafts in paediatric burn patients were analysed: 19 retroauricular FTSG (group 1) and 13 thick plantar glabrous STSG (group 2). The latter were harvested at a thickness of 0.5 mm. The resulting plantar donor defec...
Source: Burns - Category: Dermatology Source Type: research
Publication date: Available online 10 October 2019Source: BurnsAuthor(s): Varun Harish, Zhe Li, Peter K.M. MaitzAbstractBackgroundAnimal studies indicate treating burn injuries with running water (first aid) for 20 min up to 3 h after burn reduces healing time and scarring. We have previously demonstrated the benefits of first aid in minor burn injuries with respect to a reduction in wound depth, faster healing, and decreased skin grafting utilisation. The purpose of this cohort study was to assess the effect of first aid on clinical outcomes in large body surface area burn injuries (≥20%).MethodsData was ...
Source: Burns - Category: Dermatology Source Type: research
The objective of this study was to evaluate where and when pediatric burn injuries occurred. Furthermore the quality of first aid treatment, ratio of skin grafting and length of hospital stay were evaluated.The patient records of 749 children with acute burns admitted to the University Children’s Hospital of Zurich, Switzerland, were retrospectively reviewed over an 11-year period.Burn injuries in children with an immigrant background were overrepresented in our study population, whereby the proportion of immigrants decreased with rising age.Sixty-five percent of all patients received some form of first aid. Of those...
Source: Burns - Category: Dermatology Source Type: research
Publication date: Available online 20 September 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Maria Tereza Pinto Medeiros Dias, Andreisa Paiva Monteiro Bilhar, Livia Cunha Rios, Bruno Almeida Costa, Edmar Maciel Lima Júnior, Ana Paula Negreiros Nunes Alves, Zenilda Vieira Bruno, Manoel Odorico de Moraes Filho, Leonardo Robson Pinheiro Sobreira BezerraABSTRACTMayer–Rokitansky–Kuster–Hauser syndrome is the second most common cause of primary amenorrhea, trailing only gonadal dysgenesis. In patients who failed dilation therapy, neovaginoplasty is an appropriate treatment option. Sever...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Mayer –Rokitansky–Kuster–Hauser syndrome is the second most common cause of primary amenorrhea, trailing only gonadal dysgenesis. In patients who failed dilation therapy, neovaginoplasty is an appropriate treatment option. Several biomaterials have been used in this procedure, including peritoneum, amnion, skin grafts and myocutaneous flaps. Nile Tilapia Fish Skin has non-infectious microbiota, morphological structure comparable to human skin, and high in vivo bioresorption. In addition, it showed good outcomes when used as a xenograft for burn treatment.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: INSTRUMENTS AND TECHNIQUES Source Type: research
[Our Experience with Application and Cutometric Evaluation of Collagen-Elastin Dermal Substitute Matriderm® in Local Therapy of 6-Year-Old Boy with Severe Burn Trauma]. Acta Chir Orthop Traumatol Cech. 2019;86(4):286-289 Authors: Holoubek J, Lipový B Abstract The consequences of deep burns to the hands and face are the most challenging we encounter in modern reconstructive surgery. In many cases, the simple autotransplantation of full-thickness defects with split-thickness skin grafts is now considered inadequate or outdated. For this and many other reasons, the use of dermal substitution i...
Source: Acta Orthopaedica - Category: Orthopaedics Authors: Tags: Acta Chir Orthop Traumatol Cech Source Type: research
Argentum Medical’s antimicrobial dressings received an extra bit of validation after strong results from recent lab findings. The Geneva, IL-based company’s Silverlon antimicrobial dressing was found to effectively kill Candida Auris (C. Auris), the emerging “superbug” causing invasive, potentially fatal human infection in more than 30 countries, including the U.S. Argentum Medical commissioned Microbiological Consultants, an independent FDA-registered pharmaceutical testing laboratory, to establish if its metallic wound dressings can destroy C. Auris ...
Source: MDDI - Category: Medical Devices Authors: Tags: Materials Source Type: news
Since the 1980s, deep and extensive skin wounds and burns are treated with autologous Split-Thickness Skin Grafts, or Cultured Epidermal Autografts (CEAs) when donor sites are limited. However, the clinical use of CEAs often remains unsatisfactory due to poor engraftment rates, altered wound healing and reduced skin functionality.In the past few decades, Mesenchymal Stromal Cells (MSCs) have raised much attention due to their anti-inflammatory, pro-trophic and pro-remodeling capacities. More specifically, gingival MSCs have been shown to possess enhanced wound healing properties compared to other tissue sources.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
STUDY OBJECTIVE: First-aid guidelines recommend the administration of cool running water in the early management of thermal injury. Our objective is to analyze the associations between first aid and skin-grafting requirements in children with burns. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news
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