Genetic risk association of CDKN1A and RET gene SNPs with medullary thyroid carcinoma: Results from the largest MTC cohort and meta ‐analysis

ConclusionIn this largest SNP risk association study for MTC and the only risk association study of the 13 most commonly studied MTC associated SNPs in a single cohort of this rare cancer, a significant protective risk association ofCDKN1ASer31Arg SNP with MTC was shown for the first time. Meta ‐analysis identified significant risk association of all fourRET SNPs, not observed in previous meta ‐analysis.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research