Supplementation with biscuits enriched with hesperidin and naringenin is associated with an improvement of the Metabolic Syndrome induced by a cafeteria diet in rats

Publication date: October 2019Source: Journal of Functional Foods, Volume 61Author(s): Jordi Mayneris-Perxachs, Juan Maria Alcaide-Hidalgo, Esther de la Hera, Josep Maria del Bas, Lluís Arola, Antoni CaimariAbstractMetabolic syndrome (MetS) has become a major public health concern. Because of their numerous health-promoting biological properties, polyphenols are potential candidates to ameliorate MetS and, recently, the incorporation of these compounds into widely consumed foodstuffs has emerged as a potential strategy to enhance their intake. Therefore, we aimed to assess the potential beneficial effects of biscuits enriched with the citrus polyphenols hesperidin and naringenin (HN) in rats that were fed either standard chow (STD) or an obesogenic cafeteria diet (CAF) for 16 weeks. The STD and CAF groups were supplemented with either control or HN biscuits for the final 8 weeks of the study. CAF-fed rats developed MetS, characterized by obesity, insulin resistance, hypertension and dyslipidemia. HN supplementation in CAF-fed rats ameliorated hypertension and insulin resistance and significantly reduced body weight, mesenteric adiposity, total cholesterol, LDL-C and oxidative stress. Hence, HN biscuits may be a promising functional food against MetS.Graphical abstract
Source: Journal of Functional Foods - Category: Nutrition Source Type: research

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Metabolic syndrome (MetS) is defined as a group of metabolic disorders that together increase a person ’s chance of developing cardiovascular diseases, including stroke. The component disorders that comprise MetS are central obesity, high blood pressure, high blood sugar, high triglycerides, and low high-density lipoprotein cholesterol (HDL-C) [1]. Body mass index (BMI), waist circumference (WC), w aist-hip ratio (WHpR), and waist-height ratio (WHtR) are anthropometric indices that can be used to define abdominal obesity for MetS diagnosis [2].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
CONCLUSIONS: Specific metabolic syndrome components may have modest associations with ovarian cancer. These associations varied in direction and the prevalence of the components influenced the overall association between metabolic syndrome and ovarian cancer. Evaluating metabolic syndrome as a composite exposure could be misleading in ovarian cancer research, but further study of the syndrome components is warranted. PMID: 31495456 [PubMed - as supplied by publisher]
Source: Gynecologic Oncology - Category: Cancer & Oncology Authors: Tags: Gynecol Oncol Source Type: research
Abstract BACKGROUND: The severity of left ventricular (LV) remodelling is only partially related to the severity of aortic valve stenosis; additional factors, including diabetes, insulin resistance, obesity and metabolic syndrome, may play important roles. Epicardial adipose tissue (EAT), now considered as a metabolically active organ, is also linked to these factors. AIM: To analyse the association between EAT volume measured using computed tomography and LV remodelling in a prospective cohort of patients with aortic stenosis. METHODS: Consecutive asymptomatic patients with at least mild degenerative ao...
Source: Archives of Cardiovascular Diseases - Category: Cardiology Authors: Tags: Arch Cardiovasc Dis Source Type: research
The metabolic syndrome (MetS) is a clustering of abdominal obesity, diabetes and prediabetes, high cholesterol and high blood pressure, that confers an increased risk of cardiovascular disease. There is limite...
Source: Diabetology and Metabolic Syndrome - Category: Endocrinology Authors: Tags: Research Source Type: research
CONCLUSIONS: MS is correlated with CKD in both premenopausal and postmenopausal women, and the association is dependent on diabetes, hypertension, and hyperuricemia in premenopausal women but not in postmenopausal women. PMID: 31340922 [PubMed - in process]
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research
ConclusionThe frequency and severity of cardiovascular and coronary complications, particularly in chronic uremia, necessitates a correction of risk factors, some of which are inherent in chronic renal failure. The evaluation of the metabolic syndrome is a mean of screening so as to prevent its complications, in particular the cardiovascular ones, the main cause of death in these patients.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Publication date: Available online 24 July 2019Source: Archives of Cardiovascular Diseases SupplementsAuthor(s): Lamia Ghomari, Hanane Ghomari-Boukhatem, Youcef Boukhari, Malika BouchenakBackgroundThe increase in the prevalence of overweight and obesity among young people led to a surge in several risk factors, such as high blood pressure, dyslipidemia and abdominal adiposity, leading to metabolic syndrome and atherosclerosis.PurposeThe aim of the study was to assess food consumption and physical activity level (PAL), in children on the one hand, and to evaluate the cardio-metabolic risk on the other hand.Population and me...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Publication date: Available online 24 July 2019Source: Archives of Cardiovascular Diseases SupplementsAuthor(s): Amel Otmane, Mohamed Makrelouf, Akila ZenatiOxidative stress, obesity and metabolic syndrome (MS) are often combined in the pathophysiology of hypertension. The aim of this study was to quantify the plasma levels of leptin, adiponectin, and oxidized LDL in patients with essential hypertension, and to correlate these parameters with the metabolic disorders.Materials and methodsOur prospective study was carried out in 160 non-diabetic hypertensive patients, age: 57 ± 8.49 years, 118 women and 42 m...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
ConclusionThe transplant population has multiple cardiovascular risk factors. Early detection and correction of these factors must be a priority in order to improve the survival of these patients.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Publication date: Available online 13 July 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Nadia Hamjane, Fatiha Benyahya, Mohcine Bennani Mechita, Naima Ghailani Nourouti, Amina BarakatAbstractAimThe aim of this work was to study overweight and obesity and their associated complications according to obesity indicators in a population of Tangier.MethodsA total of 480 overweight and obese patients were included in this study, referred to hospital Duc Tovar of Tangier during a period of 12 months. The collection of data has been done through a questionnaire which included anthropometric...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
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