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(Natural News) PCOS, short for polycystic ovary syndrome, is a hormonal disorder that affects as many as 10 percent of women. Women suffering from PCOS mainly experience insulin resistance and have too much of the male hormone androgen. Additionally, PCOS interferes with their appearance, fertility, menstrual cycle, metabolism, and mood. Many women with this condition...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Aldosterone is the main mineralocorticoid hormone, responsible of the regulation of fluid and electrolyte balance and blood pressure. It acts also as a pro-inflammatory factor responsible of an increased cardiovascular risk, independent from blood pressure values. After the discovery of mineralocorticoid receptor (MR) in mononuclear leukocytes, further studies support its role in inflammatory and even autoimmune mechanisms underlying several diseases. In particular, recent studies reported a possible involvement of aldosterone in some gynecological conditions and diseases, characterized by inflammation, hypertension and in...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Series Type : Methylation profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Methylation profiling by high throughput sequencing Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Contributors : Danielle Hiam ; David Simar ; Rhianna Laker ; Ali Alt ıntaş ; Romain Barres ; Nigel SteptoSeries Type : Methylation profiling by high throughput sequencingOrganism : Homo sapiensTranscriptomic and genome-wide DNA methylation was performed on T helper cells using RNA-sequencing and Reduced Representation Bisulfite Sequencing, respectively. Specific genome-wide DNA methylation analysis of T helper cells from women with PCOS identified 5,581 differentially methylated CpG sites. Interestingly, functional gene ontology enrichment analysis showed that genes located at the proximity of differentially methylated C...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Methylation profiling by high throughput sequencing Homo sapiens Source Type: research
Contributors : Danielle Hiam ; David Simar ; Rhianna Laker ; Ali Alt ıntaş ; Romain Barres ; Nigel SteptoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTranscriptomic and genome-wide DNA methylation was performed on T helper cells using RNA-sequencing and Reduced Representation Bisulfite Sequencing, respectively. Specific genome-wide DNA methylation analysis of T helper cells from women with PCOS identified 5,581 differentially methylated CpG sites. Interestingly, functional gene ontology enrichment analysis showed that genes located at the proximity of differentially methylated Cp...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
This study aimed to screen critical long non-coding RNAs (lncRNAs) that might play pivotal roles in insulin resistance, which could provide candidate biomarkers and potential therapeutic targets for PCOS. Gene expression profiles of skeletal muscle in patients with PCOS accompanied by insulin resistance and healthy patients were obtained from the publicly available Gene Expression Omnibus (GEO) database. A global triple network including RNA-binding protein, mRNA, and lncRNAs was constructed based on the data from starBase. Then, we extracted an insulin resistance-associated lncRNA-mRNA network (IRLMN) by integrating the d...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Background: Hidradenitis suppurativa (HS) has been associated with various endocrine and autoimmune disorders. Although signs of hyperandrogenism are commonly observed amongst HS patients, few formal studies have assessed the relationship between HS and polycystic ovarian syndrome (PCOS).
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Introduction: Polycystic ovary syndrome (PCOS) is an idiopathic endocrine disorder that commonly presents with cutaneous signs of hyperandrogenism, including acne, hirsutism, and androgenic alopecia. Current literature on patient demographics that predict successful management of acne in PCOS is limited. The aim of this study is to assess the role of patient demographics and medications in PCOS acne management.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Introduction: Hirsutism is a common and variable aspect of polycystic ovarian syndrome (PCOS)1-3. Our study investigates what underlying factors are associated with self-reported improvement in hirsutism for patients with PCOS.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Polycystic ovary syndrome (PCOS) is a common endocrine disorder causing infertility in reproductive-age women. The cause of PCOS is not fully understood but it is thought to be influenced by environmental and ...
Source: BMC Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: Research article Source Type: research
Nature Reviews Endocrinology, Published online: 20 August 2019; doi:10.1038/s41574-019-0255-xIL-22 links gut microbiota to PCOS
Source: Nature Reviews Endocrinology - Category: Endocrinology Authors: Source Type: research
More News: Health | Hormones | Insulin | Men | Ovaries | Polycystic Ovary Syndrome | Reproduction Medicine | Women