Left atrial wall thickness is associated with the low-voltage area in patients with paroxysmal atrial fibrillation

AbstractPurposeTo identify a potential morphological marker of remodeling and electrophysiological dysfunction, we investigated if low wall thickness is associated with low-voltage areas (LVAs) in the left atrium.MethodsWall thickness was measured by computed tomography and LVA (% area with bipolar voltage  10% of segment surface area) was observed in 123 of 215 segments (57%). Segments in the low tertile of wall thickness (
Source: Journal of Interventional Cardiac Electrophysiology - Category: Cardiology Source Type: research

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Condition:   Atrial Fibrillation Intervention:   Procedure: radiofrequency ablation Sponsor:   Henan Institute of Cardiovascular Epidemiology Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Thorac cardiovasc Surg DOI: 10.1055/s-0039-1698402 Background Different ablation devices deliver the same type of energy but use individual control mechanisms to estimate efficacy. We compared patient outcome after the application of radiofrequency ablation systems, using temperature- or resistance-control in paroxysmal and persistent atrial fibrillation (AF). Methods This is an unselected all-comers study. Patients underwent standardized left atrial (paroxysmal atrial fibrillation, [PAF] n = 31) or biatrial ablation (persistent atrial fibrillation [persAF] n = 61) with bipolar R...
Source: The Thoracic and Cardiovascular Surgeon - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Original Cardiovascular Source Type: research
g A Abstract BACKGROUND:  Different ablation devices deliver the same type of energy but use individual control mechanisms to estimate efficacy. We compared patient outcome after the application of radiofrequency ablation systems, using temperature- or resistance-control in paroxysmal and persistent atrial fibrillation (AF). METHODS:  This is an unselected all-comers study. Patients underwent standardized left atrial (paroxysmal atrial fibrillation, [PAF] n = 31) or biatrial ablation (persistent atrial fibrillation [persAF] n = 61) with bipolar RF from October 2010 to Jun...
Source: The Thoracic and Cardiovascular Surgeon - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Thorac Cardiovasc Surg Source Type: research
AbstractObjectivesTo differentiate electrograms representing sites of active atrial fibrillation (AF) drivers from passive ones.BackgroundAblation of complex ‐fractionated atrial electrograms (CFAEs) is controversial due to difficulty in distinguishing CFAEs representing sites of active AF drivers from passive mechanisms. We hypothesized that active CFAE sites exhibit repetitive wavefront directionality, thereby inscribing an electrogram conformation ( Egm‐C) that is more recurrent compared with passive CFAE sites; and that can be differentiated from passive CFAEs using nonlinear recurrence quantification analysis (RQA...
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ABSTRACTObjectivesTo differentiate electrograms representing sites of active atrial fibrillation (AF) drivers from passive ones.BackgroundAblation of complex fractionated atrial electrograms (CFAEs) is controversial due to difficulty in distinguishing CFAEs representing sites of active AF drivers from passive mechanisms. We hypothesized that active CFAE sites exhibit repetitive wavefront directionality, thereby inscribing an electrogram conformation (Egm ‐C) that is more recurrent compared to passive CFAE sites; and that can be differentiated from passive CFAEs using nonlinear recurrence quantification analysis (RQA).Met...
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ‐ CLINICAL Source Type: research
No abstract available
Source: American Journal of Therapeutics - Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research
Objective : The most relevant source of signal contamination in the cardiac electrophysiology (EP) laboratory is the ubiquitous powerline interference (PLI). To reduce this perturbation, algorithms including common fixed-bandwidth and adaptive-notch filters have been proposed. Although such methods have proven to add artificial fractionation to intra-atrial electrograms (EGMs), they are still frequently used. However, such morphological alteration can conceal the accurate interpretation of EGMs, specially to evaluate the mechanisms supporting atrial fibrillation (AF), which is the most common cardiac arrhythmia. Give...
Source: Physiological Measurement - Category: Physiology Authors: Source Type: research
The objective of this study was to determine whether regions of High Frequency Ripple Activation (HFRA) observed on Ripple map provide useful ablation targets in patients with persistent AF.Methods and ResultsConsecutive patients underwent first time ablation of persistent AF (n=162) using a standard stepwise (n=105) or a Ripple map guided approach (n=57). Ripple map guided patients underwent PV antral isolation followed by ablation of HFRA sites. Acute termination of AF was observed in 91.2% of the Ripple guided patients versus 52.4% in the stepwise approach, p
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ‐ CLINICAL Source Type: research
In this report, we perform cardiac mapping with monophasic action potential (MAP) amplitude. We hypothesize that MAP amplitude (MAPA) will provide more accurate infarct sizes than other mapping modalities via increased sensitivity to distinguish healthy myocardium from scar tissue. Methods Using the left-coronary artery ligation Sprague Dawley rat model of ischemic heart failure, we investigate the accuracy of in vivo ventricular epicardial maps derived from MAPA, MAP duration to 90% repolarization (MAPD90), unipolar voltage amplitude (UVA), and bipolar voltage amplitude (BVA) when compared to gold-standard histopathologic...
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Tags: Am J Physiol Heart Circ Physiol Source Type: research
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Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
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