Correlation between incremental remifentanil doses and the Nociception Level (NOL) index response after intraoperative noxious stimuli

ConclusionsThe NOL value after noxious stimulus decreased with incremental remifentanil doses, showing a significant inverse correlation between the NOL index and opioid doses. The sensitivity and specificity of NOL to discriminate between noxious and non-noxious stimuli suggests its interesting potential as a monitor of nociception intensity during anesthesia.Trial registrationwww.clinicaltrials.gov (NCT 02884778); 27 July, 2016.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research