Laboratory evaluation of secondary causes of bone loss in Veterans with spinal cord injury and disorders

ConclusionsScreening for secondary causes of osteoporosis, particularly for hypogonadism and hypovitaminosis D, should be considered in patients with a SCI/D.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research

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CONCLUSION: When gastroenterologists encounter NAFLD/NASH patients, serum CK should be verified. If hyperCKemia, frontal baldness, a hatched face, history of cataract surgery, and grip myotonia are noted, the possibility of MD may be considered. PMID: 33033573 [PubMed]
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
In this study, in vitro antiosteoporosis activity and hepatotoxicity of P. jamasakura bark extracts were evaluated. Methods. Mouse bone marrow macrophage (BMM) cells were incubated with tartrate-resistant acid phosphate (TRAP) buffers and p-nitrophenyl phosphate and cultured with different P. jamasakura bark extracts at concentrations of 0, 6.25, 12.5, 25, and 50 μg/ml in the presence of the receptor activator of nuclear factor kappa-Β ligand (RANKL) for 6 days. The osteoclast TRAP activity and cell viability were measured. Nitric oxide (NO) assay was conducted using murine macrophage-like RAW 264.7 cells tr...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Liu X, Zheng J, Li F, Yi R, Mu J, Tan F, Zhao X Abstract A rat model of secondary osteoporosis was constructed using retinoic acid as an inducer, and the genes, proteins, and bone mass of the rats were analyzed. qPCR detection of the Wnt/β-catenin and OPG/RANK/RANKL signaling pathway-related gene expression levels showed that Lactobacillus plantarum HFY15 played a positive role in regulating both pathways. HFY15 significantly increased β-catenin, Lrp5, Lrp6, Wnt10b, OPG, RANKL, and Runx2 expression and downregulated DKK1, RANK, CTSK, TRACP, and ALP expression. Enzyme-linked immunosorbent assays f...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Study Design. Retrospective study. Objective. We identified radiological risk factors for neurological deficits in mid and low lumbar spinal fractures. Summary of Background Data. Although numerous studies have focused on radiological risk factors for neurological deficits in spinal cord injury or thoracolumbar junction area fractures, few have examined mid and low lumbar fractures at the cauda equina level. Methods. We retrospectively reviewed 71 consecutive patients who suffered acute traumatic mid and low lumbar fractures (L2–L5) corresponding to the cauda equina level, as confirmed on magnetic resonanc...
Source: Spine - Category: Orthopaedics Tags: DIAGNOSTICS Source Type: research
Publication date: December 2020Source: Journal of Functional Foods, Volume 75Author(s): Haiying Liu, Lu Huang, Jing Wang
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Publication date: Available online 8 October 2020Source: Brain, Behavior, and ImmunityAuthor(s): Yun Li, Rodney M Ritzel, Junyun He, Tuoxin Cao, Boris Sabirzhanov, Hui Li, Simon Liu, Long-Jun Wu, Junfang Wu
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
AbstractRheumatoid arthritis (RA) is a progressive autoimmune inflammatory disease affecting 1% of the population with three times as many women as men. As many as 86% of patients suffering from RA have cervical spine involvement. Synovial inflammation in the cervical spine causes instability and injuries including atlantoaxial subluxation, retroodontoid pannus formation, cranial settling, and subaxial subluxation. While many patients with cervical spine involvement are asymptomatic, symptomatic patients often present with nonspecific symptoms resulting from inflammation and additional secondary symptoms that are due to co...
Source: Neurosurgical Review - Category: Neurosurgery Source Type: research
ConclusionThis is the first population-based study to ascertain the incidence of major non-vertebral fractures in elderly Latin Americans, confirming the high frequency of the disorder. Age, prior fracture, and hip BMD were predictors of the short-term incidence of fracture.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
AbstractPurpose of ReviewThis paper seeks to review the important musculoskeletal issues that arise for pregnant and postpartum women. It outlines the background, diagnosis, and management of these musculoskeletal issues; reviews the existing and recent literature; and offers clinical opinions from the perspective of women ’s health PM&R physicians.Recent FindingsExisting and recent literature on pelvic girdle pain, lumbosacral back pain, pubic symphysis separation, transient osteoporosis, rectus diastasis, and postpartum neuropathy offer some new insights on management, which is often context-dependent. Management r...
Source: Current Physical Medicine and Rehabilitation Reports - Category: Rehabilitation Source Type: research
AbstractPurpose of Review3D cone beam imaging (CBCT) has allowed clinicians to better understand the anatomical variations of cranial anatomy. One crucial aspect of this technology plays is the understanding of alveolar bone morphology and remodeling. Variations in cortical bone thickness between individuals have been reported. No published study has analyzed the relationship between cortical bone thickness and rate of tooth movement. The aim of this study is to begin answering the question: is there an association between rate of tooth movement and cortical bone thickness?Recent FindingsTwenty-three patients underwent ext...
Source: Current Osteoporosis Reports - Category: Orthopaedics Source Type: research
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