Association between patient-reported outcomes and objective disease indices in people with NF2

Conclusions The NFTI-QOL correlated well with multiple measures of disease severity but not commonly accepted endpoints for NF2 clinical trials including total VS volume in this US cohort of patients with NF2. This suggests that the NFTI-QOL captures components of the patient experience not sufficiently represented by objective measures of disease and underscores the important and complementary role of patient-focused measures in therapeutic outcome assessment in people with NF2.

http://cp.neurology.org/cgi/content/short/9/4/322?rss=1

Source: Neurology Clinical Practice - August 11, 2019 Category: Neurology Authors: Shukla, A., Hsu, F.-C., Slobogean, B., Langmead, S., Lu, Y., Blakeley, J. O., Strowd, R. E. Tags: Quality of life, Spinal cord tumor, Nerve tumor, Clinical trials Observational study (Cohort, Case control), Neurofibromatosis Research Source Type: research