Prevalence of left ventricular systolic dysfunction in myotonic dystrophy type 1: a systematic review

Myotonic dystrophy type 1 (DM1) is the most common adult muscular dystrophy and affects between 1:3.000 and 1:8.000 individuals worldwide. Cardiac involvement is recorded in about 80% of cases.1 The prevalence of cardiac conduction abnormalities and tachyarrhythmias, both atrial and ventricular, are reasonably well described.2 –7 Data regarding the prevalence of left ventricular systolic dysfunction (LVSD) and heart failure (HF) in DM1 patients are few and conflicting.8,9

Source: Journal of Cardiac Failure - August 11, 2019 Category: Cardiology Authors: Vincenzo Russo, Simona Sperlongano, Emanuele Gallinoro, Anna Rago, Andrea Antonio Papa, Paolo Golino, Luisa Politano, Saman Nazarian, Gerardo Nigro Source Type: research