Mast cells infiltration and decreased E-cadherin expression in ketamine-induced cystitis

Conclusions: Increased mast cells in bladder wall and downregulated expression of E-cadherin junction protein in epithelial cells were probably associated with interstitial inflammation and fissures in mucosa. It implied that ketamine induced an interstitial cystitis.

Source: Toxicology Reports - December 9, 2014 Category: Toxicology Source Type: research