A clinico-microbiological study of prosthetic joint infections in an indian tertiary care hospital: Role of Universal 16S rRNA gene polymerase chain reaction and sequencing in diagnosis

Conclusions: The incidence of PJI at our Institute compares well with other published reports. Contrary to previous reports, a predominance of Gram-negative PJI's was found. The preponderance of multidrug-resistant organisms in PJI's is worrisome. The high sensitivity and specificity of the 16S PCR assay used in our study support its use in culture-negative PJI suspected cases.
Source: Indian Journal of Orthopaedics - Category: Orthopaedics Authors: Source Type: research