Human-animal hybrids now legal to grow in Japan... total HELL of GMO biologicals coming soon

(Natural News) The Japanese government has granted its approval for The University of Tokyo to proceed with a controversial stem-cell research project that aims to develop human-animal “Frankenstein” hybrid creatures, which mad scientists at the school plan to manufacture in labs from embryo to “life.” Led by renowned geneticist Dr. Hiromitsu Nakauchi, the work will...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Conclusion: These results provide a potential mechanism involving AMPK activation/ROS inhibition signaling pathway in osteogenic differentiation of BMSCs enhanced by resveratrol. It suggests that development of therapy towards ROS is an effective way for osteoporosis treatment. PMID: 31438780 [PubMed - in process]
Source: Redox Report : communications in free radical research - Category: Biochemistry Authors: Tags: Redox Rep Source Type: research
CONCLUSIONS: 1. LSCs were expressed in 63.41% of AML cases and were distributed among FAB subtypes without preference to any FAB subtype. 2. The expression of LSC phenotype was associated with poor response to induction therapy in AML patients. PMID: 31438833 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
HEALTH NOTES: Peter McCleave, 41, from Bunbury in Cheshire, was diagnosed with incurable myeloma in 2017. He now hopes to help recruit 100,000 blood donors for himself and others.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 19 August 2019Source: International Journal of PharmaceuticsAuthor(s): José L. Soriano-Ruiz, Patricia Gálvez-Martín, Elena López-Ruiz, Joaquim Suñer-Carbó, Ana C. Calpena-Campmany, Juan A. Marchal, Beatriz Clares-NaverosAbstractThe main goal of this study was the design, development and characterization of a chitosan based scaffolding substrate including three glycosaminoglycans and collagen to provide an optimal microenvironment for human mesemchymal stem cells isolated from adipose tissue (hMSCs). Chitosan scaffolds provide a moist wound environ...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
ConclusionsLPS reduced cell proliferation and VEGF secretion of PDLSCs, suggesting that periodontal pathogens might reduce the capability of PDLSCs in periodontal regeneration. Yet, LPS treated PDLSCs remained viable and VEGF secretion increased significantly over time. Further research is needed to study the potential use of PDLSCs in periodontal regeneration and the relationship of biofilm LPS accumulations.
Source: The Saudi Dental Journal - Category: Dentistry Source Type: research
Publication date: Available online 23 August 2019Source: Stem Cell ResearchAuthor(s): Lanzi Gaetana, Masneri Stefania, Ferraro Rosalba Monica, Genova Elena, Piovani Giovanna, Barisani Chiara, Pelin Marco, Stocco Gabriele, Decorti Giuliana, Bramuzzo Matteo, Giliani SilviaAbstractCrohn's disease is a debilitating and incurable chronic inflammatory bowel disease, affecting millions of individuals worldwide, with an increasing frequency. Surgery must be applicable in half of the cases often with a disabling course, and pharmacological treatments may have adverse complications. We generated three isogenic clones of iPSCs from p...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
In this study, we examined the switch in Tau splicing from fetal-only to all adult Tau isoforms during the differentiation of iPSC-derived neurons in a new 3D culture system. First, we showed that iPSC-induced neurons inside Matrigel-coated alginate capsules were able to differentiate into cortical neurons. Then, using a new assay that allowed both the qualitative and the quantitative analysis of all adult MAPT mRNA isoforms individually, we demonstrated that BrainPhys-maintained neurons expressed the 6 adult MAPT mRNA transcripts from 25 weeks of maturation, making this model highly suitable for modeling Tau pathology a...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: Available online 23 August 2019Source: Stem Cell ResearchAuthor(s): Srinivas Chatla, Wei Du, Andrew F. Wilson, Amom Ruhikanta Meetei, Qishen PangAbstractMembers of the Fanconi anemia (FA) protein family are involved in multiple cellular processes including response to DNA damage and oxidative stress. Here we show that a major FA protein, Fancd2, plays a role in mitochondrial biosynthesis through regulation of mitochondrial translation. Fancd2 interacts with Atad3 and Tufm, which are among the most frequently identified components of the mitochondrial nucleoid complex essential for mitochondrion biosynthes...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: Available online 23 August 2019Source: Stem Cell ResearchAuthor(s): Zhiqin Huang, Dan Zhang, Shang-Chih Chen, Jennifer A. Thompson, Terri McLaren, Tina Lamey, John N. De Roach, Samuel McLenachan, Fred K. ChenAbstractVariants in RCBTB1 have been implicated in inherited retinal disease (IRD). Here, we generated induced pluripotent stem cells (iPSCs) from a 45-year-old female IRD patient harbouring compound heterozygous mutations in the RCBTB1 gene. Episomal plasmids containing OCT4, SOX2, KLF4, MYCL, LIN28, shRNA for TP53 and mir302/367 microRNA were employed to conduct the reprogramming of primary dermal f...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
From stem cell therapies to editing our genes, we've seen no shortage of medical breakthroughs in recent years. But these developments also raise ethical issues. That ’s especially true when it comes to policy decisions about the kind of care people get and how precious resources are allocated. That’s the subject of the new book, "Everybody Wants to Go to Heaven but Nobody Wants to Die: Bioethics and the Transformation of Health Care in America." The book’s authors, Dr. Amy Gutmann and Dr. Jonathan Moreno, join “CBS This Morning Saturday” to discuss the ethics of the modern American health care system.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
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