The role of DEFB126 variation in male infertility and medically assisted reproduction technique outcome

ConclusionsThis sequence variation of DEFB126 may impair male reproductive function and can be related to male infertility. Interestingly, males with the del/del genotype have a normal spermiogram; however, their spermatozoa are evidently functionally impaired, which can affect IUI treatment outcome, but not treatment by IVF/ICSI.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research