Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors

Conclusion These results strongly support a role for distinct immunogenetic-related gene SNPs able to predict efficacy and safety of anti-PD1/PD-L1 therapies. The results highlight the existence of patient-specific, germinal biomarkers able predict response to checkpoint inhibitor efficacy and, possibly, to predict treatment-related adverse events.
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research