Racial Discrepancies between Caucasians and African-Americans in Peripartum Cardiomyopathy Requiring Mechanical Circulatory Support

Peripartum Cardiomyopathy (PPCM) is a rare form of cardiomyopathy diagnosed in the last month of pregnancy or up to five months postpartum in the absence of other underlying etiology. PPCM can result in cardiogenic shock or end-stage heart failure requiring mechanical circulatory support (MCS). It is unclear if there are any racial discrepancies in outcomes of patients requiring MCS.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Tags: 255 Source Type: research

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Source: Microchemical Journal - Category: Chemistry Source Type: research
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Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research
Authors: Westhoff-Bleck M, Hilfiker-Kleiner D, Pankuweit S, Schieffer B Abstract Pregnancy-associated diseases of the cardiovascular system occur in up to 10% of all pregnancies and the incidence is increasing. Besides congenital heart disease or pre-existing cardiomyopathy in the mother, the clinical focus has moved especially to peripartum cardiomyopathy (PPCM) because of the condition's dramatic clinical course and the identification of the underlying mechanisms. This review article concentrates therefore on PPCM, which occurs either in the last month of pregnancy or in the first 6 months following delivery in w...
Source: Geburtshilfe und Frauenheilkunde - Category: OBGYN Tags: Geburtshilfe Frauenheilkd Source Type: research
We present a case of a woman in her peripartum period who presented with cardiogenic shock and made complete myocardial function recovery after 4 days of extracorporeal membrane oxygenation (ECMO). Our patient's EF at the time of catastrophe was 5-10%, which improved to 60% on day 4 on ECMO. PMID: 30250348 [PubMed - in process]
Source: Journal of Extra-Corporeal Technology - Category: Cardiovascular & Thoracic Surgery Tags: J Extra Corpor Technol Source Type: research
Publication date: June 2018Source: Journal of Cardiology Cases, Volume 17, Issue 6Author(s): Takeshi Mikami, Hitoshi KamiuntenAbstractPeripartum cardiomyopathy (PPCM) is an idiopathic left ventricular dysfunction in women who are in late pregnancy or the postpartum period. PPCM is a rare but sometimes fatal disease, and mechanical circulatory support is required if heart failure is refractory to conventional therapy. A 28-year-old woman in late pregnancy was admitted to our hospital due to congestive heart failure with cardiogenic shock. Her heart rate was 200 beats per minute (sinus tachycardia), and left ventricular ejec...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Authors: Koenig T, Hilfiker-Kleiner D, Bauersachs J Abstract Peripartum cardiomyopathy (PPCM) is a rare and potentially life-threatening disease that occurs toward the end of pregnancy or in the months following delivery in previously heart-healthy women. The incidence varies widely depending on geographical region and ethnic background, with an estimated number of 1 in 1000-1500 pregnancies in Germany. The course of the disease ranges from mild forms with minor symptoms to severe forms with acute heart failure and cardiogenic shock. The understanding of the etiology of PPCM has evolved in recent years. An oxi...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Publication date: Available online 21 March 2018 Source:Journal of Cardiology Cases Author(s): Takeshi Mikami, Hitoshi Kamiunten Peripartum cardiomyopathy (PPCM) is an idiopathic left ventricular dysfunction in women who are in late pregnancy or the postpartum period. PPCM is a rare but sometimes fatal disease, and mechanical circulatory support is required if heart failure is refractory to conventional therapy. A 28-year-old woman in late pregnancy was admitted to our hospital due to congestive heart failure with cardiogenic shock. Her heart rate was 200 beats per minute (sinus tachycardia), and left ventricular ejection...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
We report a case of a woman with PPCM who developed a critical cardiogenic shock with repeated cardiopulmonary resuscitation. We show for the first time that mechanical circulatory support combined with high‐dose bromocriptine therapy to suppress systemic prolactin levels may serve as an effective therapeutic option in patients with fulminant PPCM and cardiogenic shock. Myocardial cathepsin D was overexpressed in our patient underscoring a potential role of cathepsin D‐induced cleavage of prolactin in the pathophysiology of PPCM.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Case Report Source Type: research
We report on a young multiparous woman with cardiogenic shock caused by severe PPCM who was successfully, but atypically, supported with veno-venous ECMO as a bridge to recovery immediately after the birth of her third child. PMID: 27881700 [PubMed - as supplied by publisher]
Source: Perfusion - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Perfusion Source Type: research
Peripartum cardiomyopathy (PPCM) is a rare disease, which affects women in the last month of their pregnancy or in the early puerperium without any identifiable cause of heart failure.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Letter to the editor Source Type: research
More News: African Health | Cardiogenic Shock | Cardiology | Cardiomyopathy | Heart | Heart Failure | Pregnancy