Dengue death toll rises in Malaysia, number of cases close to double

Malaysia saw a rise in deaths caused by dengue to 113 by August 3, compared to 70 cases in the same period last year, the health ministry said on Saturday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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Chen Nikos Vasilakis Sandra López-Vergès Dengue virus (DENV) is the most prevalent arbovirus in terms of human public health importance globally. In addition to DENV epidemiological surveillance, genomic surveillance may help investigators understand the epidemiological dynamics, geographic distribution, and temporal patterns of DENV circulation. Herein, we aimed to reconstruct the molecular epidemiology and phylogeny of DENV in Panama to connect the epidemiological history of DENV dispersal and circulation in Latin America. We retrospectively analyzed the epidemiological data obtained during 25 year...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
In conclusion, the new classification had a low sensitivity for identifying patients needing advanced care and for predicting morbidity and mortality. We p ropose to include decompensation of chronic diseases and thrombocytopenia-related bleeding to the category of severe dengue in the new classification to improve the sensitivity of predicting cases requiring advanced care.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
This study applied a water–energy–food (WEF) nexus analytical livelihoods model with complex systems understanding to assess rural livelihoods, health, and well-being in southern Africa, recommending tailor-made adaptation strategies for the region aimed at building resilient rural communities. The WEF nexus is a decision support tool that improves rural livelihoods through integrated resource distribution, planning, and management, and ensures inclusive socio-economic transformation and development, and addresses related sustainable development goals, particularly goals 2, 3, 6 and 7. The integrated WE...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Authors: Karabay O, Güçlü E, Şimşek A, Okan HD, Öğütlü A, Coşgun Y, Menemenlioğlu D Abstract The frequency of travel-related infections in the world has increased due to the easily and widespread use of travel facilities in the 21st century. Vector-borne diseases are an important part of infectious diseases. Dengue fever is one of the travel-related infections that has been reported increasingly in recent years through the development of diagnostic methods. The aim of this report was to present two Dengue fever cases originating from travel. There was a story of mosquito bite du...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
Publication date: Available online 16 August 2019Source: MicronAuthor(s): Lilian Mirian Oliveira de Morais, Eduardo Inocente Jussiani, João Antonio Cyrino Zequi, Paulo José dos Reis, Avacir Casanova AndrelloAbstractAedes aegypti and Aedes albopictus are vectors of several arboviruses responsible for causing dengue, chikungunya, Zika, and yellow fever viruses and microcephaly, resulting in a public health problem in several countries worldwide. Even in this scenario, studies on the morphology of mosquito eggs are still lacking. In this paper, X-ray microtomography was used to study mosquito egg morphology. Sev...
Source: Micron - Category: Biology Source Type: research
We read with interest the recent research article by Wang Ligui et al. studying the epidemic characteristics of the 2014 dengue outbreak in Guangdong Province, China.1 Dengue has recently emerged or re-emerged in many countries worldwide with the number of cases and the range of the virus increasing annually. Taiwan has experienced two large dengue outbreaks in the recent decade with high morbidity and mortality noted. Reports from Taiwan Center for Disease Control (Taiwan CDC) indicated that the major dengue epidemics occurred in the south of Taiwan, mainly in the two southern cities of Tainan and Kaohsiung.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research
CONCLUSIONS: The co-circulation of those viruses in the same area represents a risk for the development of severe infections if they spread throughout the country. Successive flavivirus infections may have an impact on disease pathogenesis, as well as on the development of safe vaccine strategies. PMID: 31411310 [PubMed - in process]
Source: Memorias do Instituto Oswaldo Cruz - Category: Infectious Diseases Authors: Tags: Mem Inst Oswaldo Cruz Source Type: research
Conclusion: Our study documents the molecular characteristics of DENV circulating in the area. Detection of heterologous DENV serotype with dominance of DENV-3 emphasises the need for regular molecular monitoring.
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research
Our main stories today: Boko Haram  terrorist survivors tell their stories; UNICEF speaks out for children adrift on the Mediterranean; UN health agency pushes to stem dengue fever in Yemen; Switzerland declines sponsorship deal with tobacco firm; new SDG Advocates on the job.
Source: UN News Centre - Health, Poverty, Food Security - Category: International Medicine & Public Health Source Type: news
In this study, we constructed a DENV2-EGFP infectious clone, established a fluorescence-based, high-throughput screening platform, and conducted a screen for anti-DENV compounds on a flavonoid-derivative library, Amongst the hits identified, ST081006 was found to be a strong inhibitor of the DENV replication. Time-course studies suggest that the presence of ST081006 is necessary to inhibit successive rounds of virus replication. Further investigations demonstrated that ST081006 affects the synthesis of both viral protein and viral RNA, and one anti-DENV mechanism is the direct inhibition of viral protein synthesis. The rep...
Source: Antiviral Therapy - Category: Virology Source Type: research
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