Monoterpene glycosides with anti-inflammatory activity from Paeoniae Radix.

Monoterpene glycosides with anti-inflammatory activity from Paeoniae Radix.
Fitoterapia. 2019 Aug 06;:104290
Authors: Li HB, Shi Y, Pang Q, Mei Y, Su Z, Yao XS, Yu Y
Abstract
Six new monoterpene glycosides, named 6'-O-nicotinoylalbiflorin (1), 4'-O-vanillylalbiflorin (2), paeonidanin L (3), paeoniflorigenin-1-O-β-d-xyloside (4), 6'-(2-hydroxypropanoyl)-paeoniflorin (5), oxylactiflorin (6), together with 16known ones (7-22) were isolated from the 70% ethanol extract of Paeoniae Radix. Their structures were elucidated based on spectroscopic analysis (1D and 2D NMR, HRESIMS, IR and UV), chemical evidences and comparison with literatures. The inhibitory effects of all the isolates were evaluated against lipopolysaccharide (LPS) stimulated PGE2 production in RAW 264.7 macrophages.
PMID: 31398448 [PubMed - as supplied by publisher]

Source: Fitoterapia - August 5, 2019 Category: Biochemistry Authors: Li HB, Shi Y, Pang Q, Mei Y, Su Z, Yao XS, Yu Y Tags: Fitoterapia Source Type: research