S. Dewar et al. Point-of-care testing by healthcare workers for detection of meticillin-resistant Staphylococcus aureus, Clostridioides difficile, and norovirus

ConclusionXpert SA Nasal Complete for MRSA detection, Xpert C. difficile, and Xpert Norovirus can be used as POCT solely by HCWs in a ward setting. Each assay was used throughout a seven-day/24 h period with potential positive impact on bed management and patient care.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

Related Links:

ConclusionEthyl acetate &Water extracts have represented potent activity against Salmonella typhi, Escherichia coli, &Staphylococcus aureus bacteria as well, provided cytotoxicity against tested cancer cell lines. These results can be explored to identify individual phyto-molecules from the extracts for anticancer &antimicrobial potentials to identify new phytomedicines.
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
FDA QIDP and Fast Track Designations Signify Significant Milestones in Allergan Commitment to Addressing Unmet Medical Needs in the Treatment of Antibiotic Resistant Infections DUBLIN, Nov. 11, 2019 -- (Healthcare Sales &Marketing Network) -- Allergan... Biopharmaceuticals, FDA Allergan, ATM-AVI, aztreonam, avibactam
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
Two new flavones, 8,4 ′-dimethoxy-6-(2-oxopropyl)-flavone (1) and 8,4 ′-dimethoxy-6-(3-hydroxypropyl)- flavone (2), were isolated from the seeds of Arctium lappa. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds1 and2 were evaluated for their anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) activity. The results showed that compounds1 and2 exhibited weak active with diameter of inhibition zone (IZD) 10.8 ± 1.0 and 9.3 ± 0.8 mm, respectively. Compounds1 and2 were also tested for antioxidant activity, and they show good an...
Source: Chemistry of Natural Compounds - Category: Chemistry Source Type: research
Possible mechanisms of the antimicrobial effects of polypeptide‑enriched Gastrodia elata Blume extracts. Mol Med Rep. 2019 Sep 25;: Authors: Kong F, Cai X, Zhai S, Wang R, Zheng X, Ma Y, Bi H, Wang D Abstract The present study aimed to evaluate the antimicrobial activity and the possible mechanisms of activity of polypeptide‑enriched Gastrodia elata extracts (GEP) against the gram‑negative bacteria Escherichia coli and Pseudomonas aeruginosa, the gram‑positive bacterium Staphylococcus aureus and the fungus Candida albicans. The antimicrobial activity of GEP was first confirmed by determining th...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
ConclusionAccording to this study MDR efflux pumps not only cause high-level resistance but also it considerably associated with over-expression of these genes. Due to the selective pressure on MRSA isolate, the enormous diversity of plasmid-encoded genes had been recorded in different regions, owing to the various numbers and types of isolates in each study or types of disinfectants for general use.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Publication date: Available online 6 November 2019Source: Microbial PathogenesisAuthor(s): Marcos Guilherme da Cunha, Janaina de Cássia Orlandi Sardi, Irlan Almeida Freires, Marcelo Franchin, Pedro Luiz RosalenAbstractThe discovery of new drug candidates, especially from natural products, remains a promising approach to overcome the alarmingly high microbial resistance rates. A major 4-phenyl coumarin named cinnamoyloxy-mammeisin (CNM) isolated from stingless bee geopropolis showed interesting biological properties; however, its antimicrobial activity against Staphylococcus aureus has never been investigated. In ord...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
In this study, copper (Cu) and zinc (Zn) as well as phosphorus (P) were co-doped into a Ti–6Al–4V titanium alloy via micro-arc oxidation (MAO). The entrance mechanisms of Cu and Zn into MAO coatings were investigated by an orthogonal experiment. The results show that Cu and Zn in Cu–Zn–P coatings separately exist mainly in the forms of Cu2O and Zn3(PO4)2. The Cu content in MAO coating increases with increasing EDTA-CuNa2 and KOH concentrations and decreasing phytic acid concentration but is nearly independent of EDTA-ZnNa2 concentration. The Zn content increases with increasing EDTA-ZnNa2 concentrat...
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research
Publication date: Available online 9 November 2019Source: Reactive and Functional PolymersAuthor(s): Felipe López-Saucedo, Noé Zúñiga-Villarreal, Guadalupe G. Flores-Rojas, Diego Martínez-Otero, Beatríz Magariños, Emilio BucioAbstractThe synthesis in water of two series of halogen Zn(II) complexes with heterocyclic ligands, containing pendant vinyl groups, has been investigated. The resulting tetrahedral ZnX2L2 complexes, where X = Cl, Br, or I, and L = N-vinylimidazole (NVI) or 4-vinylpyridine (4VP), were exposed to gamma rays in an oxygen-free atmosphere. SEM-EDS, ...
Source: Reactive and Functional Polymers - Category: Chemistry Source Type: research
CONCLUSION: Introduction of intra-saccular flow diversion can be accomplished within a care trial context. PMID: 31690151 [PubMed - as supplied by publisher]
Source: Interventional Neuroradiology - Category: Radiology Tags: Interv Neuroradiol Source Type: research
Journal of Applied Microbiology,Volume 0, Issue ja, -Not available-.
Source: Journal of Applied Microbiology - Category: Microbiology Authors: Source Type: research
More News: Clostridium Difficile | Infectious Diseases | Laboratory Medicine | MRSA | Norovirus | Staphylococcus Aureus | Study | Superbugs